6WMV

Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii with evidence of substrate binding

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008654	biological_process	phospholipid biosynthetic process
A	0016020	cellular_component	membrane
A	0016780	molecular_function	phosphotransferase activity, for other substituted phosphate groups
C	0008654	biological_process	phospholipid biosynthetic process
C	0016020	cellular_component	membrane
C	0016780	molecular_function	phosphotransferase activity, for other substituted phosphate groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue LIP A 301

Chain	Residue
A	SER132
C	ARG137
A	LYS135
A	GLU151
A	ARG152
A	PRO153
A	ARG195
A	HOH403
A	HOH409
C	TYR133

---

site_id	AC2
Number of Residues	4
Details	binding site for residue NA A 302

Chain	Residue
A	ASP31
A	THR82
A	GLY85
A	TCE305

---

site_id	AC3
Number of Residues	4
Details	binding site for residue NA A 303

Chain	Residue
A	THR34
A	ASP68
A	ASP71
A	ASP89

---

site_id	AC4
Number of Residues	4
Details	binding site for residue NA A 304

Chain	Residue
A	ASP68
A	ASP89
A	CYS92
A	ASP93

---

site_id	AC5
Number of Residues	8
Details	binding site for residue TCE A 305

Chain	Residue
A	PRO30
A	ASP31
A	GLY72
A	ALA75
A	GLY81
A	THR82
A	ASP89
A	NA302

---

site_id	AC6
Number of Residues	1
Details	binding site for residue 1PE A 306

Chain	Residue
A	ARG115

---

site_id	AC7
Number of Residues	3
Details	binding site for residue OLC A 307

Chain	Residue
A	LEU46
A	MET51
A	TRP106

---

site_id	AC8
Number of Residues	4
Details	binding site for residue OLC A 308

Chain	Residue
A	PHE170
A	ILE171
A	ALA172
A	OLC309

---

site_id	AC9
Number of Residues	1
Details	binding site for residue OLC A 309

Chain	Residue
A	OLC308

---

site_id	AD1
Number of Residues	3
Details	binding site for residue 8K6 A 310

Chain	Residue
A	ILE35
A	LEU88
C	8K6309

---

site_id	AD2
Number of Residues	1
Details	binding site for residue 8K6 A 312

Chain	Residue
A	TRP182

---

site_id	AD3
Number of Residues	1
Details	binding site for residue 8K6 A 313

Chain	Residue
A	ILE157

---

site_id	AD4
Number of Residues	1
Details	binding site for residue GOL A 314

Chain	Residue
A	GLU-73

---

site_id	AD5
Number of Residues	9
Details	binding site for residue C5P C 301

Chain	Residue
C	PRO30
C	ASP31
C	THR34
C	MET69
C	ASP71
C	GLY72
C	ALA75
C	GLY85
C	ASP89

---

site_id	AD6
Number of Residues	6
Details	binding site for residue FLC C 302

Chain	Residue
C	SER132
C	LYS135
C	GLU151
C	ARG152
C	ARG155
C	ARG195

---

site_id	AD7
Number of Residues	3
Details	binding site for residue NA C 303

Chain	Residue
C	ASP68
C	ASP89
C	ASP93

---

site_id	AD8
Number of Residues	1
Details	binding site for residue 1PE C 304

Chain	Residue
C	OLC308

---

site_id	AD9
Number of Residues	4
Details	binding site for residue OLC C 306

Chain	Residue
A	ARG83
C	GLY142
C	PRO203
C	ASP207

---

site_id	AE1
Number of Residues	5
Details	binding site for residue OLC C 307

Chain	Residue
A	ARG115
A	THR123
C	PRO50
C	TRP106
C	GOL311

---

site_id	AE2
Number of Residues	3
Details	binding site for residue OLC C 308

Chain	Residue
C	PRO178
C	VAL179
C	1PE304

---

site_id	AE3
Number of Residues	3
Details	binding site for residue 8K6 C 309

Chain	Residue
A	8K6310
C	GLY193
C	HIS197

---

site_id	AE4
Number of Residues	2
Details	binding site for residue 8K6 C 310

Chain	Residue
C	THR39
C	GOL311

---

site_id	AE5
Number of Residues	4
Details	binding site for residue GOL C 311

Chain	Residue
C	LEU46
C	MET51
C	OLC307
C	8K6310

---

Functional Information from PROSITE/UniProt

site_id	PS00379
Number of Residues	23
Details	CDP_ALCOHOL_P_TRANSF CDP-alcohol phosphatidyltransferases signature. DGamARlrsggtrfGavlDaacD

Chain	Residue	Details
A	ASP71-ASP93

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