6WMH
Next generation monomeric IgG4 Fc
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H, A | Immunoglobulin heavy constant gamma 4 | polymer | 207 | 23789.7 | 2 | UniProt (P01861) Pfam (PF07654) In PDB | Homo sapiens (Human) | Ig gamma-4 chain C region |
2 | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
H, A: 238 - 444 (UniProt: P01861)
PDB | External Database | Details |
---|---|---|
Tyr 252 | Met 132 | engineered mutation |
Thr 254 | Ser 134 | engineered mutation |
Glu 256 | Thr 136 | engineered mutation |
Asp 297 | Asn 177 | engineered mutation |
Phe 351 | Leu 231 | engineered mutation |
Glu 354 | Ser 234 | engineered mutation |
Arg 366 | Thr 246 | engineered mutation |
Lys 395 | Pro 275 | engineered mutation |
Arg 405 | Phe 285 | engineered mutation |
Glu 407 | Tyr 287 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 47579.3 | |
All* | Total formula weight | 47579.3 |