6WME

Human Sun2-KASH3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SUN domain-containing protein 2	polymer	202	22349.9	1	UniProt (Q9UH99) Pfam (PF07738)	Homo sapiens (Human)	Protein unc-84 homolog B,Rab5-interacting protein,Rab5IP,Sad1/unc-84 protein-like 2
2	B (B)	Nesprin-3	polymer	34	3617.0	1	UniProt (Q6ZMZ3) Pfam (PF10541)	Homo sapiens (Human)	KASH domain-containing protein 3,KASH3,Nuclear envelope spectrin repeat protein 3
3	C (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
4	D, E (A, B)	water	water		18.0	243	Chemie (HOH)

Sequence modifications

A: 522 - 717 (UniProt: Q9UH99)

PDB	External Database	Details
Gly 516	-	expression tag
Pro 517	-	expression tag
Gly 518	-	expression tag
Gly 519	-	expression tag
Ser 520	-	expression tag
Gly 521	-	expression tag
Asp 534	Gln 534	engineered mutation
Ile 574	Leu 574	engineered mutation
Gly 683	Thr 683	engineered mutation
Arg 684	Met 684	engineered mutation
Gly 685	Ala 685	engineered mutation

B: 948 - 975 (UniProt: Q6ZMZ3)

PDB	External Database	Details
Gly 942	-	expression tag
Pro 943	-	expression tag
Gly 944	-	expression tag
Gly 945	-	expression tag
Ser 946	-	expression tag
Gly 947	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	25966.9
Non-Polymers*	Number of molecules	1
	Total formula weight	39.1
All*	Total formula weight	26006.0

*Water molecules are not included.