6WM2
Human V-ATPase in state 1 with SidK and ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (H, I, J) | V-type proton ATPase subunit E 1 | polymer | 226 | 26183.3 | 3 | UniProt (P36543) Pfam (PF01991) | Homo sapiens (Human) | V-ATPase subunit E 1,V-ATPase 31 kDa subunit,p31,Vacuolar proton pump subunit E 1 |
| 2 | D, E, F (K, L, M) | V-type proton ATPase subunit G 1 | polymer | 118 | 13781.5 | 3 | UniProt (O75348) Pfam (PF03179) | Homo sapiens (Human) | V-ATPase subunit G 1,V-ATPase 13 kDa subunit 1,Vacuolar proton pump subunit G 1,Vacuolar proton pump subunit M16 |
| 3 | G (O) | V-type proton ATPase subunit C 1 | polymer | 382 | 43999.5 | 1 | UniProt (P21283) Pfam (PF03223) | Homo sapiens (Human) | V-ATPase subunit C 1,Vacuolar proton pump subunit C 1 |
| 4 | H (P) | V-type proton ATPase subunit H | polymer | 483 | 55949.9 | 1 | UniProt (Q9UI12) Pfam (PF03224) Pfam (PF11698) | Homo sapiens (Human) | V-ATPase subunit H,Nef-binding protein 1,NBP1,Protein VMA13 homolog,V-ATPase 50/57 kDa subunits,Vacuolar proton pump subunit H,Vacuolar proton pump subunit SFD |
| 5 | I (R) | V-type proton ATPase 116 kDa subunit a isoform 1 | polymer | 837 | 96512.4 | 1 | UniProt (Q93050) Pfam (PF01496) | Homo sapiens (Human) | V-ATPase 116 kDa isoform a1,Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit,Vacuolar adenosine triphosphatase subunit Ac116,Vacuolar proton pump subunit 1,Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 |
| 6 | J, K, L (A, B, C) | V-type proton ATPase catalytic subunit A | polymer | 617 | 68379.9 | 3 | UniProt (P38606) Pfam (PF02874) Pfam (PF16886) Pfam (PF00006) Pfam (PF22919) | Homo sapiens (Human) | V-ATPase subunit A,V-ATPase 69 kDa subunit,Vacuolar ATPase isoform VA68,Vacuolar proton pump subunit alpha |
| 7 | M, N, O (D, E, F) | V-type proton ATPase subunit B, brain isoform | polymer | 511 | 56561.5 | 3 | UniProt (P21281) Pfam (PF00006) Pfam (PF22919) Pfam (PF02874) | Homo sapiens (Human) | V-ATPase subunit B 2,Endomembrane proton pump 58 kDa subunit,HO57,Vacuolar proton pump subunit B 2 |
| 8 | P, Q, R (X, Y, Z) | SidK | polymer | 573 | 65505.3 | 3 | UniProt (A0A4T1L9X6) UniProt (by SIFTS) (Q5ZWW6) | Legionella pneumophila | |
| 9 | S (G) | V-type proton ATPase subunit D | polymer | 247 | 28311.9 | 1 | UniProt (Q9Y5K8) Pfam (PF01813) | Homo sapiens (Human) | V-ATPase subunit D,V-ATPase 28 kDa accessory protein,Vacuolar proton pump subunit D |
| 10 | T (N) | V-type proton ATPase subunit F | polymer | 119 | 13388.2 | 1 | UniProt (Q16864) Pfam (PF01990) | Homo sapiens (Human) | V-ATPase subunit F,V-ATPase 14 kDa subunit,Vacuolar proton pump subunit F |
| 11 | U (0) | V-type proton ATPase 21 kDa proteolipid subunit | polymer | 205 | 21418.2 | 1 | UniProt (Q99437) Pfam (PF00137) | Homo sapiens (Human) | V-ATPase 21 kDa proteolipid subunit,Vacuolar proton pump 21 kDa proteolipid subunit,hATPL |
| 12 | AA, BA, CA, DA, V... (1, 2, 3, 4, 5...) | V-type proton ATPase 16 kDa proteolipid subunit | polymer | 155 | 15743.7 | 9 | UniProt (P27449) Pfam (PF00137) | Homo sapiens (Human) | V-ATPase 16 kDa proteolipid subunit,Vacuolar proton pump 16 kDa proteolipid subunit |
| 13 | EA (Q) | V-type proton ATPase subunit d 1 | polymer | 351 | 40369.9 | 1 | UniProt (P61421) Pfam (PF01992) | Homo sapiens (Human) | V-ATPase subunit d 1,32 kDa accessory protein,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,p39,Vacuolar proton pump subunit d 1 |
| 14 | FA (S) | V-type proton ATPase subunit e 1 | polymer | 81 | 9380.3 | 1 | UniProt (O15342) Pfam (PF05493) | Homo sapiens (Human) | V-ATPase subunit e 1,V-ATPase 9.2 kDa membrane accessory protein,V-ATPase M9.2 subunit,Vacuolar proton pump subunit e 1 |
| 15 | GA (T) | Ribonuclease kappa | polymer | 137 | 15435.2 | 1 | UniProt (Q6P5S7) Pfam (PF23489) | Homo sapiens (Human) | RNase kappa |
| 16 | HA (U) | V-type proton ATPase subunit S1 | polymer | 470 | 52067.5 | 1 | UniProt (Q15904) Pfam (PF05827) Pfam (PF20520) | Homo sapiens (Human) | V-ATPase subunit S1,Protein XAP-3,V-ATPase Ac45 subunit,V-ATPase S1 accessory protein,Vacuolar proton pump subunit S1 |
| 17 | IA (V) | Renin receptor | polymer | 350 | 39045.9 | 1 | UniProt (O75787) Pfam (PF25294) Pfam (PF07850) | Homo sapiens (Human) | ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adapter,Embryonic liver differentiation factor 10,N14F,Renin/prorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,V-ATPase M8.9 subunit |
| 18 | JA (W) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 998.9 | 1 | In PDB GlyTouCan (G48558GR) | |||
| 19 | KA (a) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose | branched | 836.7 | 1 | In PDB GlyTouCan (G50886AE) | |||
| 20 | LA, MA, NA, OA, PA (u, b, c, d, s) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 21 | QA (r) | alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1883.7 | 1 | In PDB GlyTouCan (G71069MN) | |||
| 22 | CB, KB, RA, WB (0, 5, R, V) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (304) PubChem (176980071) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (18640088) PubChem (1715243) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (1715244) PubChem (23423981) PubChem (45044259) PubChem (638019) PubChem (49853509) PubChem (50990013) PubChem (44654663) PubChem (52934537) PubChem (56621683) PubChem (1549081) PubChem (1553803) PubChem (46937002) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (59274407) PubChem (5283629) PubChem (5284644) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (5315842) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (6419195) PubChem (5997) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (89951918) PubChem (90224410) PubChem (91298236) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (1551269) PubChem (90070115) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (117965027) PubChem (6432564) PubChem (101624109) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (132837164) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (124225449) PubChem (124429284) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (138967089) PubChem (139566851) PubChem (130459183) PubChem (131992107) PubChem (15939944) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (171828367) PubChem (173516975) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 23 | SA (R) | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE | non-polymer | 455.4 | 1 | Chemie (PSF) PubChem (17754227) PubChem (44354119) PubChem (9547083) PubChem (9547088) PubChem (101771308) PubChem (15409343) | |||
| 24 | EB, FB, HB, LB, MB... (0, 2, 5, 6, 7...) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 13 | Chemie (PTY) PubChem (446872) PubChem (3330137) | |||
| 25 | AB, BB, DB, GB, IB... (0, 1, 3, U, R...) | tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium | non-polymer | 787.1 | 10 | Chemie (WSS) PubChem (21145399) PubChem (448653) PubChem (5313462) PubChem (6335427) PubChem (6540623) PubChem (94287) PubChem (103588) PubChem (5313476) PubChem (5313461) PubChem (5313475) PubChem (124511141) PubChem (124511142) | |||
| 26 | UB, WA (U, R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 27 | XA (R) | methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate | non-polymer | 534.6 | 1 | Chemie (WJP) PubChem (155804591) | |||
| 28 | YA (C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 29 | JB (3) | (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid | non-polymer | 497.4 | 1 | Chemie (WJS) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 35 |
| Total formula weight | 1248806.6 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5841.3 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 21317.4 | |
| All* | Total formula weight | 1275965.3 |
