6WM2

Human V-ATPase in state 1 with SidK and ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000139	cellular_component	Golgi membrane
0	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
0	0005515	molecular_function	protein binding
0	0005765	cellular_component	lysosomal membrane
0	0005768	cellular_component	endosome
0	0005886	cellular_component	plasma membrane
0	0006811	biological_process	monoatomic ion transport
0	0007035	biological_process	vacuolar acidification
0	0007042	biological_process	lysosomal lumen acidification
0	0010008	cellular_component	endosome membrane
0	0015078	molecular_function	proton transmembrane transporter activity
0	0016020	cellular_component	membrane
0	0016241	biological_process	regulation of macroautophagy
0	0030665	cellular_component	clathrin-coated vesicle membrane
0	0030670	cellular_component	phagocytic vesicle membrane
0	0031410	cellular_component	cytoplasmic vesicle
0	0033176	cellular_component	proton-transporting V-type ATPase complex
0	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
0	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
0	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
0	0048388	biological_process	endosomal lumen acidification
0	0051452	biological_process	intracellular pH reduction
0	0061795	biological_process	Golgi lumen acidification
0	1902600	biological_process	proton transmembrane transport
1	0000139	cellular_component	Golgi membrane
1	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
1	0005515	molecular_function	protein binding
1	0005765	cellular_component	lysosomal membrane
1	0005886	cellular_component	plasma membrane
1	0005925	cellular_component	focal adhesion
1	0006811	biological_process	monoatomic ion transport
1	0007035	biological_process	vacuolar acidification
1	0007042	biological_process	lysosomal lumen acidification
1	0010008	cellular_component	endosome membrane
1	0015078	molecular_function	proton transmembrane transporter activity
1	0015986	biological_process	proton motive force-driven ATP synthesis
1	0016020	cellular_component	membrane
1	0016241	biological_process	regulation of macroautophagy
1	0030177	biological_process	positive regulation of Wnt signaling pathway
1	0030665	cellular_component	clathrin-coated vesicle membrane
1	0030670	cellular_component	phagocytic vesicle membrane
1	0030672	cellular_component	synaptic vesicle membrane
1	0031410	cellular_component	cytoplasmic vesicle
1	0031625	molecular_function	ubiquitin protein ligase binding
1	0033176	cellular_component	proton-transporting V-type ATPase complex
1	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
1	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
1	0035577	cellular_component	azurophil granule membrane
1	0045202	cellular_component	synapse
1	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
1	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
1	0048388	biological_process	endosomal lumen acidification
1	0051452	biological_process	intracellular pH reduction
1	0061795	biological_process	Golgi lumen acidification
1	0070062	cellular_component	extracellular exosome
1	0070821	cellular_component	tertiary granule membrane
1	0097401	biological_process	synaptic vesicle lumen acidification
1	0098588	cellular_component	bounding membrane of organelle
1	0101003	cellular_component	ficolin-1-rich granule membrane
1	1902600	biological_process	proton transmembrane transport
2	0000139	cellular_component	Golgi membrane
2	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
2	0005515	molecular_function	protein binding
2	0005765	cellular_component	lysosomal membrane
2	0005886	cellular_component	plasma membrane
2	0005925	cellular_component	focal adhesion
2	0006811	biological_process	monoatomic ion transport
2	0007035	biological_process	vacuolar acidification
2	0007042	biological_process	lysosomal lumen acidification
2	0010008	cellular_component	endosome membrane
2	0015078	molecular_function	proton transmembrane transporter activity
2	0015986	biological_process	proton motive force-driven ATP synthesis
2	0016020	cellular_component	membrane
2	0016241	biological_process	regulation of macroautophagy
2	0030177	biological_process	positive regulation of Wnt signaling pathway
2	0030665	cellular_component	clathrin-coated vesicle membrane
2	0030670	cellular_component	phagocytic vesicle membrane
2	0030672	cellular_component	synaptic vesicle membrane
2	0031410	cellular_component	cytoplasmic vesicle
2	0031625	molecular_function	ubiquitin protein ligase binding
2	0033176	cellular_component	proton-transporting V-type ATPase complex
2	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
2	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
2	0035577	cellular_component	azurophil granule membrane
2	0045202	cellular_component	synapse
2	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
2	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
2	0048388	biological_process	endosomal lumen acidification
2	0051452	biological_process	intracellular pH reduction
2	0061795	biological_process	Golgi lumen acidification
2	0070062	cellular_component	extracellular exosome
2	0070821	cellular_component	tertiary granule membrane
2	0097401	biological_process	synaptic vesicle lumen acidification
2	0098588	cellular_component	bounding membrane of organelle
2	0101003	cellular_component	ficolin-1-rich granule membrane
2	1902600	biological_process	proton transmembrane transport
3	0000139	cellular_component	Golgi membrane
3	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
3	0005515	molecular_function	protein binding
3	0005765	cellular_component	lysosomal membrane
3	0005886	cellular_component	plasma membrane
3	0005925	cellular_component	focal adhesion
3	0006811	biological_process	monoatomic ion transport
3	0007035	biological_process	vacuolar acidification
3	0007042	biological_process	lysosomal lumen acidification
3	0010008	cellular_component	endosome membrane
3	0015078	molecular_function	proton transmembrane transporter activity
3	0015986	biological_process	proton motive force-driven ATP synthesis
3	0016020	cellular_component	membrane
3	0016241	biological_process	regulation of macroautophagy
3	0030177	biological_process	positive regulation of Wnt signaling pathway
3	0030665	cellular_component	clathrin-coated vesicle membrane
3	0030670	cellular_component	phagocytic vesicle membrane
3	0030672	cellular_component	synaptic vesicle membrane
3	0031410	cellular_component	cytoplasmic vesicle
3	0031625	molecular_function	ubiquitin protein ligase binding
3	0033176	cellular_component	proton-transporting V-type ATPase complex
3	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
3	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
3	0035577	cellular_component	azurophil granule membrane
3	0045202	cellular_component	synapse
3	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
3	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
3	0048388	biological_process	endosomal lumen acidification
3	0051452	biological_process	intracellular pH reduction
3	0061795	biological_process	Golgi lumen acidification
3	0070062	cellular_component	extracellular exosome
3	0070821	cellular_component	tertiary granule membrane
3	0097401	biological_process	synaptic vesicle lumen acidification
3	0098588	cellular_component	bounding membrane of organelle
3	0101003	cellular_component	ficolin-1-rich granule membrane
3	1902600	biological_process	proton transmembrane transport
4	0000139	cellular_component	Golgi membrane
4	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
4	0005515	molecular_function	protein binding
4	0005765	cellular_component	lysosomal membrane
4	0005886	cellular_component	plasma membrane
4	0005925	cellular_component	focal adhesion
4	0006811	biological_process	monoatomic ion transport
4	0007035	biological_process	vacuolar acidification
4	0007042	biological_process	lysosomal lumen acidification
4	0010008	cellular_component	endosome membrane
4	0015078	molecular_function	proton transmembrane transporter activity
4	0015986	biological_process	proton motive force-driven ATP synthesis
4	0016020	cellular_component	membrane
4	0016241	biological_process	regulation of macroautophagy
4	0030177	biological_process	positive regulation of Wnt signaling pathway
4	0030665	cellular_component	clathrin-coated vesicle membrane
4	0030670	cellular_component	phagocytic vesicle membrane
4	0030672	cellular_component	synaptic vesicle membrane
4	0031410	cellular_component	cytoplasmic vesicle
4	0031625	molecular_function	ubiquitin protein ligase binding
4	0033176	cellular_component	proton-transporting V-type ATPase complex
4	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
4	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
4	0035577	cellular_component	azurophil granule membrane
4	0045202	cellular_component	synapse
4	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
4	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
4	0048388	biological_process	endosomal lumen acidification
4	0051452	biological_process	intracellular pH reduction
4	0061795	biological_process	Golgi lumen acidification
4	0070062	cellular_component	extracellular exosome
4	0070821	cellular_component	tertiary granule membrane
4	0097401	biological_process	synaptic vesicle lumen acidification
4	0098588	cellular_component	bounding membrane of organelle
4	0101003	cellular_component	ficolin-1-rich granule membrane
4	1902600	biological_process	proton transmembrane transport
5	0000139	cellular_component	Golgi membrane
5	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
5	0005515	molecular_function	protein binding
5	0005765	cellular_component	lysosomal membrane
5	0005886	cellular_component	plasma membrane
5	0005925	cellular_component	focal adhesion
5	0006811	biological_process	monoatomic ion transport
5	0007035	biological_process	vacuolar acidification
5	0007042	biological_process	lysosomal lumen acidification
5	0010008	cellular_component	endosome membrane
5	0015078	molecular_function	proton transmembrane transporter activity
5	0015986	biological_process	proton motive force-driven ATP synthesis
5	0016020	cellular_component	membrane
5	0016241	biological_process	regulation of macroautophagy
5	0030177	biological_process	positive regulation of Wnt signaling pathway
5	0030665	cellular_component	clathrin-coated vesicle membrane
5	0030670	cellular_component	phagocytic vesicle membrane
5	0030672	cellular_component	synaptic vesicle membrane
5	0031410	cellular_component	cytoplasmic vesicle
5	0031625	molecular_function	ubiquitin protein ligase binding
5	0033176	cellular_component	proton-transporting V-type ATPase complex
5	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
5	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
5	0035577	cellular_component	azurophil granule membrane
5	0045202	cellular_component	synapse
5	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
5	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
5	0048388	biological_process	endosomal lumen acidification
5	0051452	biological_process	intracellular pH reduction
5	0061795	biological_process	Golgi lumen acidification
5	0070062	cellular_component	extracellular exosome
5	0070821	cellular_component	tertiary granule membrane
5	0097401	biological_process	synaptic vesicle lumen acidification
5	0098588	cellular_component	bounding membrane of organelle
5	0101003	cellular_component	ficolin-1-rich granule membrane
5	1902600	biological_process	proton transmembrane transport
6	0000139	cellular_component	Golgi membrane
6	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
6	0005515	molecular_function	protein binding
6	0005765	cellular_component	lysosomal membrane
6	0005886	cellular_component	plasma membrane
6	0005925	cellular_component	focal adhesion
6	0006811	biological_process	monoatomic ion transport
6	0007035	biological_process	vacuolar acidification
6	0007042	biological_process	lysosomal lumen acidification
6	0010008	cellular_component	endosome membrane
6	0015078	molecular_function	proton transmembrane transporter activity
6	0015986	biological_process	proton motive force-driven ATP synthesis
6	0016020	cellular_component	membrane
6	0016241	biological_process	regulation of macroautophagy
6	0030177	biological_process	positive regulation of Wnt signaling pathway
6	0030665	cellular_component	clathrin-coated vesicle membrane
6	0030670	cellular_component	phagocytic vesicle membrane
6	0030672	cellular_component	synaptic vesicle membrane
6	0031410	cellular_component	cytoplasmic vesicle
6	0031625	molecular_function	ubiquitin protein ligase binding
6	0033176	cellular_component	proton-transporting V-type ATPase complex
6	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
6	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
6	0035577	cellular_component	azurophil granule membrane
6	0045202	cellular_component	synapse
6	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
6	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
6	0048388	biological_process	endosomal lumen acidification
6	0051452	biological_process	intracellular pH reduction
6	0061795	biological_process	Golgi lumen acidification
6	0070062	cellular_component	extracellular exosome
6	0070821	cellular_component	tertiary granule membrane
6	0097401	biological_process	synaptic vesicle lumen acidification
6	0098588	cellular_component	bounding membrane of organelle
6	0101003	cellular_component	ficolin-1-rich granule membrane
6	1902600	biological_process	proton transmembrane transport
7	0000139	cellular_component	Golgi membrane
7	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
7	0005515	molecular_function	protein binding
7	0005765	cellular_component	lysosomal membrane
7	0005886	cellular_component	plasma membrane
7	0005925	cellular_component	focal adhesion
7	0006811	biological_process	monoatomic ion transport
7	0007035	biological_process	vacuolar acidification
7	0007042	biological_process	lysosomal lumen acidification
7	0010008	cellular_component	endosome membrane
7	0015078	molecular_function	proton transmembrane transporter activity
7	0015986	biological_process	proton motive force-driven ATP synthesis
7	0016020	cellular_component	membrane
7	0016241	biological_process	regulation of macroautophagy
7	0030177	biological_process	positive regulation of Wnt signaling pathway
7	0030665	cellular_component	clathrin-coated vesicle membrane
7	0030670	cellular_component	phagocytic vesicle membrane
7	0030672	cellular_component	synaptic vesicle membrane
7	0031410	cellular_component	cytoplasmic vesicle
7	0031625	molecular_function	ubiquitin protein ligase binding
7	0033176	cellular_component	proton-transporting V-type ATPase complex
7	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
7	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
7	0035577	cellular_component	azurophil granule membrane
7	0045202	cellular_component	synapse
7	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
7	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
7	0048388	biological_process	endosomal lumen acidification
7	0051452	biological_process	intracellular pH reduction
7	0061795	biological_process	Golgi lumen acidification
7	0070062	cellular_component	extracellular exosome
7	0070821	cellular_component	tertiary granule membrane
7	0097401	biological_process	synaptic vesicle lumen acidification
7	0098588	cellular_component	bounding membrane of organelle
7	0101003	cellular_component	ficolin-1-rich granule membrane
7	1902600	biological_process	proton transmembrane transport
8	0000139	cellular_component	Golgi membrane
8	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
8	0005515	molecular_function	protein binding
8	0005765	cellular_component	lysosomal membrane
8	0005886	cellular_component	plasma membrane
8	0005925	cellular_component	focal adhesion
8	0006811	biological_process	monoatomic ion transport
8	0007035	biological_process	vacuolar acidification
8	0007042	biological_process	lysosomal lumen acidification
8	0010008	cellular_component	endosome membrane
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0016020	cellular_component	membrane
8	0016241	biological_process	regulation of macroautophagy
8	0030177	biological_process	positive regulation of Wnt signaling pathway
8	0030665	cellular_component	clathrin-coated vesicle membrane
8	0030670	cellular_component	phagocytic vesicle membrane
8	0030672	cellular_component	synaptic vesicle membrane
8	0031410	cellular_component	cytoplasmic vesicle
8	0031625	molecular_function	ubiquitin protein ligase binding
8	0033176	cellular_component	proton-transporting V-type ATPase complex
8	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
8	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
8	0035577	cellular_component	azurophil granule membrane
8	0045202	cellular_component	synapse
8	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
8	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
8	0048388	biological_process	endosomal lumen acidification
8	0051452	biological_process	intracellular pH reduction
8	0061795	biological_process	Golgi lumen acidification
8	0070062	cellular_component	extracellular exosome
8	0070821	cellular_component	tertiary granule membrane
8	0097401	biological_process	synaptic vesicle lumen acidification
8	0098588	cellular_component	bounding membrane of organelle
8	0101003	cellular_component	ficolin-1-rich granule membrane
8	1902600	biological_process	proton transmembrane transport
9	0000139	cellular_component	Golgi membrane
9	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
9	0005515	molecular_function	protein binding
9	0005765	cellular_component	lysosomal membrane
9	0005886	cellular_component	plasma membrane
9	0005925	cellular_component	focal adhesion
9	0006811	biological_process	monoatomic ion transport
9	0007035	biological_process	vacuolar acidification
9	0007042	biological_process	lysosomal lumen acidification
9	0010008	cellular_component	endosome membrane
9	0015078	molecular_function	proton transmembrane transporter activity
9	0015986	biological_process	proton motive force-driven ATP synthesis
9	0016020	cellular_component	membrane
9	0016241	biological_process	regulation of macroautophagy
9	0030177	biological_process	positive regulation of Wnt signaling pathway
9	0030665	cellular_component	clathrin-coated vesicle membrane
9	0030670	cellular_component	phagocytic vesicle membrane
9	0030672	cellular_component	synaptic vesicle membrane
9	0031410	cellular_component	cytoplasmic vesicle
9	0031625	molecular_function	ubiquitin protein ligase binding
9	0033176	cellular_component	proton-transporting V-type ATPase complex
9	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
9	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
9	0035577	cellular_component	azurophil granule membrane
9	0045202	cellular_component	synapse
9	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
9	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
9	0048388	biological_process	endosomal lumen acidification
9	0051452	biological_process	intracellular pH reduction
9	0061795	biological_process	Golgi lumen acidification
9	0070062	cellular_component	extracellular exosome
9	0070821	cellular_component	tertiary granule membrane
9	0097401	biological_process	synaptic vesicle lumen acidification
9	0098588	cellular_component	bounding membrane of organelle
9	0101003	cellular_component	ficolin-1-rich granule membrane
9	1902600	biological_process	proton transmembrane transport
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005765	cellular_component	lysosomal membrane
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0005902	cellular_component	microvillus
A	0006811	biological_process	monoatomic ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0007035	biological_process	vacuolar acidification
A	0007042	biological_process	lysosomal lumen acidification
A	0010008	cellular_component	endosome membrane
A	0016020	cellular_component	membrane
A	0016241	biological_process	regulation of macroautophagy
A	0016324	cellular_component	apical plasma membrane
A	0016469	cellular_component	proton-transporting two-sector ATPase complex
A	0016887	molecular_function	ATP hydrolysis activity
A	0030133	cellular_component	transport vesicle
A	0030141	cellular_component	secretory granule
A	0030665	cellular_component	clathrin-coated vesicle membrane
A	0031410	cellular_component	cytoplasmic vesicle
A	0033176	cellular_component	proton-transporting V-type ATPase complex
A	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
A	0036295	biological_process	cellular response to increased oxygen levels
A	0042592	biological_process	homeostatic process
A	0046034	biological_process	ATP metabolic process
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	0048388	biological_process	endosomal lumen acidification
A	0051452	biological_process	intracellular pH reduction
A	0061795	biological_process	Golgi lumen acidification
A	0070062	cellular_component	extracellular exosome
A	0097401	biological_process	synaptic vesicle lumen acidification
A	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
A	1902600	biological_process	proton transmembrane transport
A	1904949	cellular_component	ATPase complex
B	0000139	cellular_component	Golgi membrane
B	0000166	molecular_function	nucleotide binding
B	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005764	cellular_component	lysosome
B	0005765	cellular_component	lysosomal membrane
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0005902	cellular_component	microvillus
B	0006811	biological_process	monoatomic ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0007035	biological_process	vacuolar acidification
B	0007042	biological_process	lysosomal lumen acidification
B	0010008	cellular_component	endosome membrane
B	0016020	cellular_component	membrane
B	0016241	biological_process	regulation of macroautophagy
B	0016324	cellular_component	apical plasma membrane
B	0016469	cellular_component	proton-transporting two-sector ATPase complex
B	0016887	molecular_function	ATP hydrolysis activity
B	0030133	cellular_component	transport vesicle
B	0030141	cellular_component	secretory granule
B	0030665	cellular_component	clathrin-coated vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0033176	cellular_component	proton-transporting V-type ATPase complex
B	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
B	0036295	biological_process	cellular response to increased oxygen levels
B	0042592	biological_process	homeostatic process
B	0046034	biological_process	ATP metabolic process
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	0048388	biological_process	endosomal lumen acidification
B	0051452	biological_process	intracellular pH reduction
B	0061795	biological_process	Golgi lumen acidification
B	0070062	cellular_component	extracellular exosome
B	0097401	biological_process	synaptic vesicle lumen acidification
B	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
B	1902600	biological_process	proton transmembrane transport
B	1904949	cellular_component	ATPase complex
C	0000139	cellular_component	Golgi membrane
C	0000166	molecular_function	nucleotide binding
C	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005764	cellular_component	lysosome
C	0005765	cellular_component	lysosomal membrane
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0005902	cellular_component	microvillus
C	0006811	biological_process	monoatomic ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0007035	biological_process	vacuolar acidification
C	0007042	biological_process	lysosomal lumen acidification
C	0010008	cellular_component	endosome membrane
C	0016020	cellular_component	membrane
C	0016241	biological_process	regulation of macroautophagy
C	0016324	cellular_component	apical plasma membrane
C	0016469	cellular_component	proton-transporting two-sector ATPase complex
C	0016887	molecular_function	ATP hydrolysis activity
C	0030133	cellular_component	transport vesicle
C	0030141	cellular_component	secretory granule
C	0030665	cellular_component	clathrin-coated vesicle membrane
C	0031410	cellular_component	cytoplasmic vesicle
C	0033176	cellular_component	proton-transporting V-type ATPase complex
C	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
C	0036295	biological_process	cellular response to increased oxygen levels
C	0042592	biological_process	homeostatic process
C	0046034	biological_process	ATP metabolic process
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	0048388	biological_process	endosomal lumen acidification
C	0051452	biological_process	intracellular pH reduction
C	0061795	biological_process	Golgi lumen acidification
C	0070062	cellular_component	extracellular exosome
C	0097401	biological_process	synaptic vesicle lumen acidification
C	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
C	1902600	biological_process	proton transmembrane transport
C	1904949	cellular_component	ATPase complex
D	0000166	molecular_function	nucleotide binding
D	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
D	0001726	cellular_component	ruffle
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005765	cellular_component	lysosomal membrane
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0005902	cellular_component	microvillus
D	0006811	biological_process	monoatomic ion transport
D	0007035	biological_process	vacuolar acidification
D	0015078	molecular_function	proton transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0016241	biological_process	regulation of macroautophagy
D	0016324	cellular_component	apical plasma membrane
D	0030665	cellular_component	clathrin-coated vesicle membrane
D	0030672	cellular_component	synaptic vesicle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
D	0042470	cellular_component	melanosome
D	0045202	cellular_component	synapse
D	0046034	biological_process	ATP metabolic process
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	0070062	cellular_component	extracellular exosome
D	0097401	biological_process	synaptic vesicle lumen acidification
D	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
D	1902600	biological_process	proton transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
E	0001726	cellular_component	ruffle
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005765	cellular_component	lysosomal membrane
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0005902	cellular_component	microvillus
E	0006811	biological_process	monoatomic ion transport
E	0007035	biological_process	vacuolar acidification
E	0015078	molecular_function	proton transmembrane transporter activity
E	0016020	cellular_component	membrane
E	0016241	biological_process	regulation of macroautophagy
E	0016324	cellular_component	apical plasma membrane
E	0030665	cellular_component	clathrin-coated vesicle membrane
E	0030672	cellular_component	synaptic vesicle membrane
E	0031410	cellular_component	cytoplasmic vesicle
E	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
E	0042470	cellular_component	melanosome
E	0045202	cellular_component	synapse
E	0046034	biological_process	ATP metabolic process
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	0070062	cellular_component	extracellular exosome
E	0097401	biological_process	synaptic vesicle lumen acidification
E	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
E	1902600	biological_process	proton transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
F	0001726	cellular_component	ruffle
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005765	cellular_component	lysosomal membrane
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0005902	cellular_component	microvillus
F	0006811	biological_process	monoatomic ion transport
F	0007035	biological_process	vacuolar acidification
F	0015078	molecular_function	proton transmembrane transporter activity
F	0016020	cellular_component	membrane
F	0016241	biological_process	regulation of macroautophagy
F	0016324	cellular_component	apical plasma membrane
F	0030665	cellular_component	clathrin-coated vesicle membrane
F	0030672	cellular_component	synaptic vesicle membrane
F	0031410	cellular_component	cytoplasmic vesicle
F	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
F	0042470	cellular_component	melanosome
F	0045202	cellular_component	synapse
F	0046034	biological_process	ATP metabolic process
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	0070062	cellular_component	extracellular exosome
F	0097401	biological_process	synaptic vesicle lumen acidification
F	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
F	1902600	biological_process	proton transmembrane transport
G	0000139	cellular_component	Golgi membrane
G	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
G	0005515	molecular_function	protein binding
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005765	cellular_component	lysosomal membrane
G	0005813	cellular_component	centrosome
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0005886	cellular_component	plasma membrane
G	0005929	cellular_component	cilium
G	0006811	biological_process	monoatomic ion transport
G	0007035	biological_process	vacuolar acidification
G	0007042	biological_process	lysosomal lumen acidification
G	0010008	cellular_component	endosome membrane
G	0016020	cellular_component	membrane
G	0016241	biological_process	regulation of macroautophagy
G	0030030	biological_process	cell projection organization
G	0030665	cellular_component	clathrin-coated vesicle membrane
G	0031410	cellular_component	cytoplasmic vesicle
G	0033176	cellular_component	proton-transporting V-type ATPase complex
G	0035579	cellular_component	specific granule membrane
G	0042995	cellular_component	cell projection
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	0048388	biological_process	endosomal lumen acidification
G	0051452	biological_process	intracellular pH reduction
G	0060271	biological_process	cilium assembly
G	0061512	biological_process	protein localization to cilium
G	0061795	biological_process	Golgi lumen acidification
G	0070062	cellular_component	extracellular exosome
G	0097401	biological_process	synaptic vesicle lumen acidification
G	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
G	1902600	biological_process	proton transmembrane transport
H	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005765	cellular_component	lysosomal membrane
H	0005768	cellular_component	endosome
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0005902	cellular_component	microvillus
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0016241	biological_process	regulation of macroautophagy
H	0016324	cellular_component	apical plasma membrane
H	0016469	cellular_component	proton-transporting two-sector ATPase complex
H	0030665	cellular_component	clathrin-coated vesicle membrane
H	0030672	cellular_component	synaptic vesicle membrane
H	0031410	cellular_component	cytoplasmic vesicle
H	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
H	0045202	cellular_component	synapse
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	0051117	molecular_function	ATPase binding
H	0070062	cellular_component	extracellular exosome
H	0097401	biological_process	synaptic vesicle lumen acidification
H	1902600	biological_process	proton transmembrane transport
I	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005765	cellular_component	lysosomal membrane
I	0005768	cellular_component	endosome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0005902	cellular_component	microvillus
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0016241	biological_process	regulation of macroautophagy
I	0016324	cellular_component	apical plasma membrane
I	0016469	cellular_component	proton-transporting two-sector ATPase complex
I	0030665	cellular_component	clathrin-coated vesicle membrane
I	0030672	cellular_component	synaptic vesicle membrane
I	0031410	cellular_component	cytoplasmic vesicle
I	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
I	0045202	cellular_component	synapse
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	0051117	molecular_function	ATPase binding
I	0070062	cellular_component	extracellular exosome
I	0097401	biological_process	synaptic vesicle lumen acidification
I	1902600	biological_process	proton transmembrane transport
J	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005765	cellular_component	lysosomal membrane
J	0005768	cellular_component	endosome
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0005902	cellular_component	microvillus
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0016241	biological_process	regulation of macroautophagy
J	0016324	cellular_component	apical plasma membrane
J	0016469	cellular_component	proton-transporting two-sector ATPase complex
J	0030665	cellular_component	clathrin-coated vesicle membrane
J	0030672	cellular_component	synaptic vesicle membrane
J	0031410	cellular_component	cytoplasmic vesicle
J	0033178	cellular_component	proton-transporting two-sector ATPase complex, catalytic domain
J	0045202	cellular_component	synapse
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	0051117	molecular_function	ATPase binding
J	0070062	cellular_component	extracellular exosome
J	0097401	biological_process	synaptic vesicle lumen acidification
J	1902600	biological_process	proton transmembrane transport
K	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
K	0005515	molecular_function	protein binding
K	0005765	cellular_component	lysosomal membrane
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006811	biological_process	monoatomic ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0016020	cellular_component	membrane
K	0016241	biological_process	regulation of macroautophagy
K	0016324	cellular_component	apical plasma membrane
K	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
K	0016887	molecular_function	ATP hydrolysis activity
K	0030672	cellular_component	synaptic vesicle membrane
K	0033176	cellular_component	proton-transporting V-type ATPase complex
K	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
K	0036295	biological_process	cellular response to increased oxygen levels
K	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
K	0051117	molecular_function	ATPase binding
K	0070062	cellular_component	extracellular exosome
K	0097401	biological_process	synaptic vesicle lumen acidification
K	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
K	1902600	biological_process	proton transmembrane transport
K	1904949	cellular_component	ATPase complex
L	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
L	0005515	molecular_function	protein binding
L	0005765	cellular_component	lysosomal membrane
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006811	biological_process	monoatomic ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0016020	cellular_component	membrane
L	0016241	biological_process	regulation of macroautophagy
L	0016324	cellular_component	apical plasma membrane
L	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
L	0016887	molecular_function	ATP hydrolysis activity
L	0030672	cellular_component	synaptic vesicle membrane
L	0033176	cellular_component	proton-transporting V-type ATPase complex
L	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
L	0036295	biological_process	cellular response to increased oxygen levels
L	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
L	0051117	molecular_function	ATPase binding
L	0070062	cellular_component	extracellular exosome
L	0097401	biological_process	synaptic vesicle lumen acidification
L	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
L	1902600	biological_process	proton transmembrane transport
L	1904949	cellular_component	ATPase complex
M	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
M	0005515	molecular_function	protein binding
M	0005765	cellular_component	lysosomal membrane
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006811	biological_process	monoatomic ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0016020	cellular_component	membrane
M	0016241	biological_process	regulation of macroautophagy
M	0016324	cellular_component	apical plasma membrane
M	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
M	0016887	molecular_function	ATP hydrolysis activity
M	0030672	cellular_component	synaptic vesicle membrane
M	0033176	cellular_component	proton-transporting V-type ATPase complex
M	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
M	0036295	biological_process	cellular response to increased oxygen levels
M	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
M	0051117	molecular_function	ATPase binding
M	0070062	cellular_component	extracellular exosome
M	0097401	biological_process	synaptic vesicle lumen acidification
M	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
M	1902600	biological_process	proton transmembrane transport
M	1904949	cellular_component	ATPase complex
N	0000139	cellular_component	Golgi membrane
N	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
N	0005515	molecular_function	protein binding
N	0005765	cellular_component	lysosomal membrane
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0006811	biological_process	monoatomic ion transport
N	0007035	biological_process	vacuolar acidification
N	0007042	biological_process	lysosomal lumen acidification
N	0010008	cellular_component	endosome membrane
N	0015078	molecular_function	proton transmembrane transporter activity
N	0016020	cellular_component	membrane
N	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
N	0030665	cellular_component	clathrin-coated vesicle membrane
N	0030672	cellular_component	synaptic vesicle membrane
N	0031410	cellular_component	cytoplasmic vesicle
N	0033176	cellular_component	proton-transporting V-type ATPase complex
N	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
N	0034220	biological_process	monoatomic ion transmembrane transport
N	0042625	molecular_function	ATPase-coupled ion transmembrane transporter activity
N	0045202	cellular_component	synapse
N	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
N	0048388	biological_process	endosomal lumen acidification
N	0051452	biological_process	intracellular pH reduction
N	0061795	biological_process	Golgi lumen acidification
N	0070062	cellular_component	extracellular exosome
N	0097401	biological_process	synaptic vesicle lumen acidification
N	1902600	biological_process	proton transmembrane transport
O	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
O	0005515	molecular_function	protein binding
O	0005765	cellular_component	lysosomal membrane
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006811	biological_process	monoatomic ion transport
O	0015078	molecular_function	proton transmembrane transporter activity
O	0016020	cellular_component	membrane
O	0016241	biological_process	regulation of macroautophagy
O	0016469	cellular_component	proton-transporting two-sector ATPase complex
O	0030665	cellular_component	clathrin-coated vesicle membrane
O	0030672	cellular_component	synaptic vesicle membrane
O	0031410	cellular_component	cytoplasmic vesicle
O	0033176	cellular_component	proton-transporting V-type ATPase complex
O	0033180	cellular_component	proton-transporting V-type ATPase, V1 domain
O	0045177	cellular_component	apical part of cell
O	0045202	cellular_component	synapse
O	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
O	0070062	cellular_component	extracellular exosome
O	0097401	biological_process	synaptic vesicle lumen acidification
O	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
O	1902600	biological_process	proton transmembrane transport
O	1904949	cellular_component	ATPase complex
P	0000139	cellular_component	Golgi membrane
P	0000221	cellular_component	vacuolar proton-transporting V-type ATPase, V1 domain
P	0005515	molecular_function	protein binding
P	0005765	cellular_component	lysosomal membrane
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006811	biological_process	monoatomic ion transport
P	0006897	biological_process	endocytosis
P	0007035	biological_process	vacuolar acidification
P	0007042	biological_process	lysosomal lumen acidification
P	0010008	cellular_component	endosome membrane
P	0016020	cellular_component	membrane
P	0016241	biological_process	regulation of macroautophagy
P	0016887	molecular_function	ATP hydrolysis activity
P	0030234	molecular_function	enzyme regulator activity
P	0030665	cellular_component	clathrin-coated vesicle membrane
P	0031410	cellular_component	cytoplasmic vesicle
P	0033176	cellular_component	proton-transporting V-type ATPase complex
P	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
P	0048388	biological_process	endosomal lumen acidification
P	0051452	biological_process	intracellular pH reduction
P	0061795	biological_process	Golgi lumen acidification
P	0070062	cellular_component	extracellular exosome
P	0098850	cellular_component	extrinsic component of synaptic vesicle membrane
P	1902600	biological_process	proton transmembrane transport
Q	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
Q	0005515	molecular_function	protein binding
Q	0005764	cellular_component	lysosome
Q	0005765	cellular_component	lysosomal membrane
Q	0005769	cellular_component	early endosome
Q	0005813	cellular_component	centrosome
Q	0006811	biological_process	monoatomic ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0007034	biological_process	vacuolar transport
Q	0007035	biological_process	vacuolar acidification
Q	0008021	cellular_component	synaptic vesicle
Q	0010008	cellular_component	endosome membrane
Q	0016020	cellular_component	membrane
Q	0016241	biological_process	regulation of macroautophagy
Q	0016324	cellular_component	apical plasma membrane
Q	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
Q	0030030	biological_process	cell projection organization
Q	0030665	cellular_component	clathrin-coated vesicle membrane
Q	0030670	cellular_component	phagocytic vesicle membrane
Q	0030672	cellular_component	synaptic vesicle membrane
Q	0031410	cellular_component	cytoplasmic vesicle
Q	0032991	cellular_component	protein-containing complex
Q	0033176	cellular_component	proton-transporting V-type ATPase complex
Q	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
Q	0033181	cellular_component	plasma membrane proton-transporting V-type ATPase complex
Q	0036295	biological_process	cellular response to increased oxygen levels
Q	0042592	biological_process	homeostatic process
Q	0043679	cellular_component	axon terminus
Q	0044877	molecular_function	protein-containing complex binding
Q	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
Q	0060271	biological_process	cilium assembly
Q	0070062	cellular_component	extracellular exosome
Q	0097401	biological_process	synaptic vesicle lumen acidification
Q	1902600	biological_process	proton transmembrane transport
R	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0005765	cellular_component	lysosomal membrane
R	0005794	cellular_component	Golgi apparatus
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0006811	biological_process	monoatomic ion transport
R	0007035	biological_process	vacuolar acidification
R	0007042	biological_process	lysosomal lumen acidification
R	0010008	cellular_component	endosome membrane
R	0016020	cellular_component	membrane
R	0016241	biological_process	regulation of macroautophagy
R	0016471	cellular_component	vacuolar proton-transporting V-type ATPase complex
R	0016607	cellular_component	nuclear speck
R	0030665	cellular_component	clathrin-coated vesicle membrane
R	0030667	cellular_component	secretory granule membrane
R	0030670	cellular_component	phagocytic vesicle membrane
R	0030672	cellular_component	synaptic vesicle membrane
R	0031410	cellular_component	cytoplasmic vesicle
R	0033176	cellular_component	proton-transporting V-type ATPase complex
R	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
R	0042470	cellular_component	melanosome
R	0045202	cellular_component	synapse
R	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
R	0048388	biological_process	endosomal lumen acidification
R	0048471	cellular_component	perinuclear region of cytoplasm
R	0051117	molecular_function	ATPase binding
R	0070062	cellular_component	extracellular exosome
R	0097401	biological_process	synaptic vesicle lumen acidification
R	0101003	cellular_component	ficolin-1-rich granule membrane
R	1902600	biological_process	proton transmembrane transport
S	0005515	molecular_function	protein binding
S	0005765	cellular_component	lysosomal membrane
S	0006811	biological_process	monoatomic ion transport
S	0007035	biological_process	vacuolar acidification
S	0010008	cellular_component	endosome membrane
S	0016020	cellular_component	membrane
S	0016241	biological_process	regulation of macroautophagy
S	0030670	cellular_component	phagocytic vesicle membrane
S	0033176	cellular_component	proton-transporting V-type ATPase complex
S	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
S	0042625	molecular_function	ATPase-coupled ion transmembrane transporter activity
S	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
S	0055085	biological_process	transmembrane transport
S	1902600	biological_process	proton transmembrane transport
T	0000139	cellular_component	Golgi membrane
T	0000220	cellular_component	vacuolar proton-transporting V-type ATPase, V0 domain
T	0004518	molecular_function	nuclease activity
T	0004519	molecular_function	endonuclease activity
T	0004521	molecular_function	RNA endonuclease activity
T	0005515	molecular_function	protein binding
T	0005765	cellular_component	lysosomal membrane
T	0005886	cellular_component	plasma membrane
T	0006811	biological_process	monoatomic ion transport
T	0006897	biological_process	endocytosis
T	0006898	biological_process	receptor-mediated endocytosis
T	0007035	biological_process	vacuolar acidification
T	0007042	biological_process	lysosomal lumen acidification
T	0010008	cellular_component	endosome membrane
T	0012505	cellular_component	endomembrane system
T	0016020	cellular_component	membrane
T	0016787	molecular_function	hydrolase activity
T	0019065	biological_process	receptor-mediated endocytosis of virus by host cell
T	0030665	cellular_component	clathrin-coated vesicle membrane
T	0031410	cellular_component	cytoplasmic vesicle
T	0033176	cellular_component	proton-transporting V-type ATPase complex
T	0048388	biological_process	endosomal lumen acidification
T	0051452	biological_process	intracellular pH reduction
T	0061795	biological_process	Golgi lumen acidification
T	0090304	biological_process	nucleic acid metabolic process
T	1902600	biological_process	proton transmembrane transport
V	0016020	cellular_component	membrane
V	0038023	molecular_function	signaling receptor activity
X	0005515	molecular_function	protein binding
X	0141159	biological_process	symbiont-mediated suppression of host phagosome acidification
Y	0005515	molecular_function	protein binding
Y	0141159	biological_process	symbiont-mediated suppression of host phagosome acidification
Z	0005515	molecular_function	protein binding
Z	0141159	biological_process	symbiont-mediated suppression of host phagosome acidification

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PSVNWLISYS

Chain	Residue	Details
A	PRO446-SER455
D	PRO390-SER399

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P50518","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylthreonine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2005","submissionDatabase":"UniProtKB","authors":["Kanor S.","Bienvenut W.V.","Quadroni M."]}},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1150
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	127
Details	Topological domain: {"description":"Vacuolar","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	415
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9Z1G4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9Z1G4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GalNAc...) asparagine","evidences":[{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6WLZ","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6WM2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	188
Details	Topological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Site: {"description":"Essential for proton translocation","evidences":[{"source":"UniProtKB","id":"Q2TA24","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	9
Details	Site: {"description":"Essential for proton translocation","evidences":[{"source":"PubMed","id":"36074901","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P51863","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P51863","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	6
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WLW","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6WM2","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WLW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33065002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WM4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---