6WKJ
Crystal structure of pentalenene synthase mutant F76H complexed with 12,13-difluorofarnesyl diphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Pentalenene synthase | polymer | 337 | 38041.4 | 2 | UniProt (Q55012) Pfam (PF19086) In PDB | Streptomyces sp. | PS,Pentalenolactone biosynthesis protein A,Sesquiterpene cyclase,Sesquiterpene synthase |
| 2 | A | (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate | non-polymer | 418.3 | 1 | Chemie (FDF) | |||
| 3 | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: Q55012)
| PDB | External Database | Details |
|---|---|---|
| His 76 | Phe 76 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76082.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 418.3 | |
| All* | Total formula weight | 76501.1 |
