6WK1
SETD3 in Complex with an Actin Peptide with His73 Replaced with Methionine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (Y, Z) | Actin, cytoplasmic 2 | polymer | 23 | 2861.3 | 2 | UniProt (P63261) | Homo sapiens | Gamma-actin |
| 2 | B, D (A, B) | Actin-histidine N-methyltransferase | polymer | 594 | 67342.0 | 2 | UniProt (Q86TU7) Pfam (PF00856) Pfam (PF09273) | Homo sapiens (Human) | SET domain-containing protein 3,hSETD3 |
| 3 | E, H, I, J, LA... (Y, A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | AA, AB, BA, BB, CA... (A, B, Y) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 46 | Chemie (EDO) | |||
| 5 | G, NA (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 6 | DA (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | HB, IB, JB, KB (Y, A, Z, B) | water | water | 18.0 | 601 | Chemie (HOH) |
Sequence modifications
Y, Z: 66 - 88 (UniProt: P63261)
| PDB | External Database | Details |
|---|---|---|
| Met 73 | His 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 140406.7 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 4235.6 | |
| All* | Total formula weight | 144642.2 |
