6WJJ
Anthrax octamer prechannel bound to full-length lethal factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, D, E | Protective antigen | polymer | 735 | 82511.3 | 4 | UniProt (P13423) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) Pfam (PF20835) In PDB | Bacillus anthracis | PA,Anthrax toxins translocating protein,PA-83,PA83 |
2 | B, F, G, H | Protective antigen | polymer | 735 | 82639.7 | 4 | UniProt (P13423) Pfam (PF20835) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) In PDB | Bacillus anthracis | PA,Anthrax toxins translocating protein,PA-83,PA83 |
3 | L, I, J, K | Lethal factor | polymer | 776 | 90356.8 | 4 | UniProt (I3XID8) Pfam (PF07737) Pfam (PF09156) UniProt (by SIFTS) (P15917) In PDB | Bacillus anthracis | |
4 | G, E, H, A, B... | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
5 | J, K, L, I | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | J, K, L, I | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, C, D, E: 1 - 735 (UniProt: P13423)
B, F, G, H: 1 - 735 (UniProt: P13423)
PDB | External Database | Details |
---|---|---|
Asp 121 | Asn 153 | conflict |
Leu 161 | Arg 193 | conflict |
Glu 162 | Lys 194 | conflict |
Val 163 | - | insertion |
Leu 164 | - | insertion |
Phe 165 | - | insertion |
Gln 166 | Lys 195 | conflict |
Gly 167 | Arg 196 | conflict |
Gly 245 | Lys 274 | engineered mutation |
Asn 252 | Arg 281 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Leu 161 | Arg 193 | conflict |
Glu 162 | Lys 194 | conflict |
Val 163 | - | insertion |
Leu 164 | - | insertion |
Phe 165 | - | insertion |
Gln 166 | Lys 195 | conflict |
Gly 167 | Arg 196 | conflict |
Lys 512 | Asp 541 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 1022031.3 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 1287.1 | |
All* | Total formula weight | 1023318.4 |