6WJF
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion | polymer | 405 | 47338.0 | 2 | UniProt (P25685) UniProt (P17612) Pfam (PF00226) Pfam (PF00069) In PDB | Homo sapiens (Human) | DnaJ protein homolog 1,Heat shock 40 kDa protein 1,Heat shock protein 40,Human DnaJ protein 1,hDj-1,PKA C-alpha |
2 | C, D | cAMP-dependent protein kinase type II-beta regulatory subunit | polymer | 416 | 46177.9 | 2 | UniProt (P12369) Pfam (PF02197) Pfam (PF00027) In PDB | Rattus norvegicus (Rat) |
Sequence modifications
A, B: 1 - 69 (UniProt: P25685)
A, B: 70 - 405 (UniProt: P17612)
A, B: 70 - 405 (UniProt: P17612)
PDB | External Database | Details |
---|---|---|
Gly 273 | Ala 211 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 187031.7 | |
All* | Total formula weight | 187031.7 |