6WIW

c-Src Bound to ATP-Competitive Inhibitor I14

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Proto-oncogene tyrosine-protein kinase Src	polymer	286	32726.6	2	UniProt (P00523) Pfam (PF07714)	Gallus gallus (Chicken)	Proto-oncogene c-Src,pp60c-src,p60-Src
2	C, D (A, B)	N-(3-{[4-amino-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl}-4-methylphenyl)acetamide	non-polymer		363.4	2	Chemie (I14)
3	E, F (A, B)	water	water		18.0	240	Chemie (HOH)

Sequence modifications

A, B: 251 - 533 (UniProt: P00523)

PDB	External Database	Details
Gly 248	-	expression tag
His 249	-	expression tag
Met 250	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65453.3
Non-Polymers*	Number of molecules	2
	Total formula weight	726.8
All*	Total formula weight	66180.1

*Water molecules are not included.