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6WIB

Next generation monomeric IgG4 Fc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Immunoglobulin heavy constant gamma 4polymer21023848.01UniProt (P01861)
Pfam (PF07654)
Homo sapiens (Human)Ig gamma-4 chain C region
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched1463.31In PDB
GlyTouCan (G80858MF)
3C, D, E
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
4F
(A)
waterwater18.014Chemie (HOH)
Sequence modifications
A: 235 - 444 (UniProt: P01861)
PDBExternal DatabaseDetails
Phe 351Leu 231engineered mutation
Arg 366Thr 246engineered mutation
Lys 395Pro 275engineered mutation
Arg 405Phe 285engineered mutation
Glu 407Tyr 287engineered mutation
Cys 432Leu 312engineered mutation
Ser 433His 313engineered mutation
Trp 434Asn 314engineered mutation
Leu 436Tyr 316engineered mutation
Cys 437Thr 317engineered mutation
-Gln 318deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23848.0
BranchedNumber of molecules1
Total formula weight1463.3
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight25507.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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