6WHK
Minimally mutated anti-influenza broadly neutralizing antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin HA1 chain | polymer | 230 | 25981.9 | 1 | UniProt (B4UPF7) Pfam (PF00509) | Influenza A virus (A/Beijing/262/1995(H1N1)) | |
| 2 | B (C) | Fab Heavy Chain | polymer | 240 | 25869.1 | 1 | Homo sapiens | ||
| 3 | C (B) | Fab Light Chain | polymer | 219 | 22929.3 | 1 | Homo sapiens | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 6 | F, G, H (A, C, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 48 - 267 (UniProt: B4UPF7)
| PDB | External Database | Details |
|---|---|---|
| Ala 46 | - | expression tag |
| Ser 47 | - | expression tag |
| Gly 268 | - | expression tag |
| Ser 269 | - | expression tag |
| Leu 270 | - | expression tag |
| Glu 271 | - | expression tag |
| Val 272 | - | expression tag |
| Leu 273 | - | expression tag |
| Phe 274 | - | expression tag |
| Gln 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74780.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 354.4 | |
| All* | Total formula weight | 75559.3 |
