6WHE
Structure of phosphomimetic Rab8a GTPase (T72E) in the GTP-bound state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ras-related protein Rab-8A | polymer | 184 | 21077.2 | 2 | UniProt (P61006) Pfam (PF00071) In PDB | Homo sapiens (Human) | Oncogene c-mel |
2 | A, B | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 181 (UniProt: P61006)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Leu 67 | Gln 67 | engineered mutation |
Glu 72 | Thr 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42154.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1187.1 | |
All* | Total formula weight | 43341.4 |