6WHE
Structure of phosphomimetic Rab8a GTPase (T72E) in the GTP-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related protein Rab-8A | polymer | 184 | 21077.2 | 2 | UniProt (P61006) Pfam (PF00071) | Homo sapiens (Human) | Oncogene c-mel |
| 2 | C, E (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 3 | D, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 181 (UniProt: P61006)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 67 | Gln 67 | engineered mutation |
| Glu 72 | Thr 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42154.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1187.1 | |
| All* | Total formula weight | 43341.4 |
