6WH8
The structure of NTMT1 in complex with compound BM-30
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | polymer | 241 | 27320.1 | 2 | UniProt (Q9BV86) Pfam (PF05891) In PDB | Homo sapiens (Human) | Alpha N-terminal protein methyltransferase 1A,Methyltransferase-like protein 11A,N-terminal RCC1 methyltransferase,X-Pro-Lys N-terminal protein methyltransferase 1A,NTM1A |
2 | C, D | 4HP-PRO-LYS-ARG-NH2, BM-30 | polymer | 5 | 533.6 | 2 | BIRD (PRD_002315) | synthetic construct | |
3 | B, A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
4 | water | water | 18.0 | 560 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 223 (UniProt: Q9BV86)
PDB | External Database | Details |
---|---|---|
Met -17 | - | expression tag |
Gly -16 | - | expression tag |
Ser -15 | - | expression tag |
Ser -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
Ser -7 | - | expression tag |
Ser -6 | - | expression tag |
Gly -5 | - | expression tag |
Leu -4 | - | expression tag |
Val -3 | - | expression tag |
Pro -2 | - | expression tag |
Arg -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 55707.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 768.8 | |
All* | Total formula weight | 56476.3 |