6WEP
Crystal structure of TS-DHFR from Cryptosporidium hominis with Apo-TS site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 521 | 60262.5 | 2 | UniProt (A0A0S4TER9) Pfam (PF00186) Pfam (PF00303) In PDB | Cryptosporidium hominis | |
| 2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | A, B | METHOTREXATE | non-polymer | 454.4 | 2 | Chemie (MTX) | |||
| 4 | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120525.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2399.7 | |
| All* | Total formula weight | 122924.8 |
