6WE2
Human PARP14 (ARTD8), catalytic fragment in complex with RBN012759
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Isoform 1 of Protein mono-ADP-ribosyltransferase PARP14 | polymer | 189 | 21654.0 | 2 | UniProt (Q460N5) Pfam (PF00644) | Homo sapiens (Human) | ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2,Poly [ADP-ribose] polymerase 14,PARP-14 |
2 | C, E (A, B) | 7-(cyclopropylmethoxy)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one | non-polymer | 378.5 | 2 | Chemie (XBA) | |||
3 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | F, G (A, B) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43308.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 819.0 | |
All* | Total formula weight | 44127.1 |