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6WE2

Human PARP14 (ARTD8), catalytic fragment in complex with RBN012759

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Isoform 1 of Protein mono-ADP-ribosyltransferase PARP14polymer18921654.02UniProt (Q460N5)
Pfam (PF00644)
Homo sapiens (Human)ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2,Poly [ADP-ribose] polymerase 14,PARP-14
2C, E
(A, B)
7-(cyclopropylmethoxy)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-onenon-polymer378.52Chemie (XBA)
3D
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4F, G
(A, B)
waterwater18.018Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43308.1
Non-Polymers*Number of molecules3
Total formula weight819.0
All*Total formula weight44127.1
*Water molecules are not included.

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PDB entries from 2025-07-23

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