6WDO
Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, G, I, M... (G, A, E, I, O...) | Calcium uniporter protein, mitochondrial | polymer | 273 | 32014.9 | 6 | UniProt (Q8NE86) Pfam (PF04678) | Homo sapiens (Human) | HsMCU,Coiled-coil domain-containing protein 109A |
| 2 | B, D, F, H, J... (H, D, B, F, J...) | Essential MCU regulator, mitochondrial | polymer | 53 | 5864.1 | 8 | UniProt (Q9H4I9) Pfam (PF10161) | Homo sapiens (Human) | Single-pass membrane protein with aspartate-rich tail 1,mitochondrial |
| 3 | C, K (C, K) | Calcium uniporter protein, mitochondrial | polymer | 268 | 31406.2 | 2 | UniProt (Q8NE86) Pfam (PF04678) | Homo sapiens (Human) | HsMCU,Coiled-coil domain-containing protein 109A |
| 4 | Q, S (Q, S) | Calcium uptake protein 1, mitochondrial | polymer | 339 | 39058.5 | 2 | UniProt (Q9BPX6) Pfam (PF13202) | Homo sapiens (Human) | Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1 |
| 5 | R, T (R, T) | Calcium uptake protein 2, mitochondrial | polymer | 310 | 36682.0 | 2 | UniProt (Q8IYU8) | Homo sapiens (Human) | EF-hand domain-containing family member A1 |
| 6 | U, V (A, I) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 453295.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 453375.6 |
