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6WDN

Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACalcium uptake protein 2, mitochondrialpolymer33539755.61UniProt (Q8IYU8)
In PDB
Homo sapiens (Human)EF-hand domain-containing family member A1
2BCalcium uptake protein 1, mitochondrialpolymer36341900.91UniProt (Q9BPX6)
Pfam (PF13202)
In PDB
Homo sapiens (Human)Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1
3F, D, H, JEssential MCU regulator, mitochondrialpolymer515667.84UniProt (Q9H4I9)
Pfam (PF10161)
In PDB
Homo sapiens (Human)Single-pass membrane protein with aspartate-rich tail 1,mitochondrial
4C, G, I, ECalcium uniporter protein, mitochondrialpolymer17821256.54UniProt (Q8NE86)
Pfam (PF04678)
In PDB
Homo sapiens (Human)HsMCU,Coiled-coil domain-containing protein 109A
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight189353.9
All*Total formula weight189353.9
*Water molecules are not included.

222624

PDB entries from 2024-07-17

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