6WBW
Structure of Human HDAC2 in complex with an ethyl ketone inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Histone deacetylase 2 | polymer | 376 | 43062.0 | 3 | UniProt (Q92769) Pfam (PF00850) | Homo sapiens (Human) | HD2 |
| 2 | D, K, Q (A, B, C) | N-{(1S)-7,7-dihydroxy-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]nonyl}-1-methylazetidine-3-carboxamide | non-polymer | 495.6 | 3 | Chemie (TV1) | |||
| 3 | E, L, R (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F, G, M, N, S... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 5 | H, I, J, O, P... (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 6 | V, W, X (A, B, C) | water | water | 18.0 | 1117 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 129186.0 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2560.3 | |
| All* | Total formula weight | 131746.2 |
