Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004407 | molecular_function | histone deacetylase activity |
| B | 0004407 | molecular_function | histone deacetylase activity |
| C | 0004407 | molecular_function | histone deacetylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue TV1 A 401 |
| Chain | Residue |
| A | GLY28 |
| A | PHE151 |
| A | ASP177 |
| A | HIS179 |
| A | PHE206 |
| A | ASP265 |
| A | LEU272 |
| A | GLY302 |
| A | TYR304 |
| A | ZN402 |
| A | HOH716 |
| A | HIS29 |
| A | PRO30 |
| A | MET31 |
| A | GLU99 |
| A | ASP100 |
| A | HIS141 |
| A | HIS142 |
| A | GLY150 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 402 |
| Chain | Residue |
| A | ASP177 |
| A | HIS179 |
| A | ASP265 |
| A | TV1401 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP175 |
| A | ASP177 |
| A | HIS179 |
| A | SER198 |
| A | PHE199 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | PHE188 |
| A | THR191 |
| A | VAL194 |
| A | TYR223 |
| A | HOH547 |
| A | HOH680 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 405 |
| Chain | Residue |
| A | ASP19 |
| A | ASN22 |
| A | TYR23 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 406 |
| Chain | Residue |
| A | GLU336 |
| A | GLY339 |
| A | HOH693 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 407 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for residue TV1 B 401 |
| Chain | Residue |
| B | GLY28 |
| B | HIS29 |
| B | PRO30 |
| B | MET31 |
| B | ASP100 |
| B | HIS141 |
| B | HIS142 |
| B | GLY150 |
| B | PHE151 |
| B | ASP177 |
| B | HIS179 |
| B | PHE206 |
| B | ASP265 |
| B | LEU272 |
| B | GLY302 |
| B | TYR304 |
| B | ZN402 |
| B | HOH589 |
| B | HOH739 |
| B | HOH757 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 402 |
| Chain | Residue |
| B | ASP177 |
| B | HIS179 |
| B | ASP265 |
| B | TV1401 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| B | ASP175 |
| B | ASP177 |
| B | HIS179 |
| B | SER198 |
| B | PHE199 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 404 |
| Chain | Residue |
| B | PHE188 |
| B | THR191 |
| B | VAL194 |
| B | TYR223 |
| B | HOH655 |
| B | HOH749 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 405 |
| Chain | Residue |
| B | ASN350 |
| B | THR352 |
| B | HOH727 |
| C | PEG405 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 406 |
| Chain | Residue |
| A | ARG127 |
| B | ASP19 |
| B | ASN22 |
| B | TYR23 |
| B | ASP105 |
| site_id | AD5 |
| Number of Residues | 18 |
| Details | binding site for residue TV1 C 401 |
| Chain | Residue |
| C | LEU272 |
| C | GLY302 |
| C | TYR304 |
| C | ZN402 |
| C | HOH723 |
| C | GLY28 |
| C | HIS29 |
| C | PRO30 |
| C | MET31 |
| C | ASP100 |
| C | HIS141 |
| C | HIS142 |
| C | GLY150 |
| C | PHE151 |
| C | ASP177 |
| C | HIS179 |
| C | PHE206 |
| C | ASP265 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 402 |
| Chain | Residue |
| C | ASP177 |
| C | HIS179 |
| C | ASP265 |
| C | TV1401 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue CA C 403 |
| Chain | Residue |
| C | PHE188 |
| C | THR191 |
| C | VAL194 |
| C | TYR223 |
| C | HOH538 |
| C | HOH703 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 404 |
| Chain | Residue |
| C | ASP175 |
| C | ASP177 |
| C | HIS179 |
| C | SER198 |
| C | PHE199 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue PEG C 405 |
| Chain | Residue |
| B | ASN350 |
| B | PEG405 |
| C | LEU165 |
| C | LYS166 |
| C | GLN169 |
| C | ARG193 |
| C | HOH566 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS142 | |
| B | HIS142 | |
| C | HIS142 | |
| Chain | Residue | Details |
| A | PHE188 | |
| A | THR191 | |
| A | VAL194 | |
| A | SER198 | |
| A | PHE199 | |
| A | ASP265 | |
| B | ASP175 | |
| B | ASP177 | |
| B | HIS179 | |
| B | PHE188 | |
| B | THR191 | |
| B | VAL194 | |
| B | SER198 | |
| B | PHE199 | |
| B | ASP265 | |
| C | ASP175 | |
| C | ASP177 | |
| C | HIS179 | |
| C | PHE188 | |
| C | THR191 | |
| C | VAL194 | |
| C | SER198 | |
| C | PHE199 | |
| C | ASP265 | |
| A | ASP175 | |
| A | ASP177 | |
| A | HIS179 | |
| Chain | Residue | Details |
| A | TYR223 | |
| B | TYR223 | |
| C | TYR223 | |
| Chain | Residue | Details |
| A | LYS75 | |
| B | LYS75 | |
| C | LYS75 | |
| Chain | Residue | Details |
| B | LYS221 | |
| A | LYS221 | |
| C | LYS221 | |
| Chain | Residue | Details |
| A | CYS262 | |
| A | CYS274 | |
| B | CYS262 | |
| B | CYS274 | |
| C | CYS262 | |
| C | CYS274 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS75 | |
| B | LYS75 | |
| C | LYS75 | |
