6W9K
Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with Prednisolone and PGC1a coregulator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glucocorticoid Receptor | polymer | 249 | 28702.4 | 1 | UniProt (A0A1X8XLE9) Pfam (PF00104) In PDB | synthetic construct | |
| 2 | B | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | polymer | 10 | 1097.4 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PPARGC-1-alpha,Ligand effect modulator 6 |
| 3 | A | prednisolone | non-polymer | 360.4 | 1 | Chemie (TUA) | Prednisolone | ||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: -2 - 245 (UniProt: A0A1X8XLE9)
| PDB | External Database | Details |
|---|---|---|
| Lys 246 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29799.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 452.5 | |
| All* | Total formula weight | 30252.4 |
