6W7I
LmFPPS mutant T164W in complex with 476A, IPP & Ca
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Farnesyl pyrophosphate synthase | polymer | 362 | 41130.3 | 2 | UniProt (Q4QBL1) Pfam (PF00348) | Leishmania major | |
| 2 | C, D, E, J, K... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 3 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | G, M (A, B) | ISOPENTYL PYROPHOSPHATE | non-polymer | 248.1 | 2 | Chemie (IPR) | |||
| 5 | H, N (A, B) | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium | non-polymer | 324.2 | 2 | Chemie (476) | |||
| 6 | I (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | O, P (A, B) | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 362 (UniProt: Q4QBL1)
| PDB | External Database | Details |
|---|---|---|
| Fme 1 | - | expression tag |
| Trp 164 | Thr 164 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82260.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1550.3 | |
| All* | Total formula weight | 83810.9 |
