6W7I
LmFPPS mutant T164W in complex with 476A, IPP & Ca
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| A | 0004337 | molecular_function | geranyltranstransferase activity |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| B | 0004337 | molecular_function | geranyltranstransferase activity |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ASP250 |
| A | 476406 |
| A | HOH504 |
| A | HOH540 |
| A | HOH599 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | HOH531 |
| A | HOH669 |
| A | ASP98 |
| A | ASP102 |
| A | CA403 |
| A | 476406 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP98 |
| A | ASP102 |
| A | CA402 |
| A | 476406 |
| A | HOH526 |
| A | HOH536 |
| A | HOH665 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | ASP254 |
| A | GLY266 |
| A | ASP268 |
| A | ILE269 |
| A | GLU270 |
| A | VAL305 |
| A | LYS309 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue IPR A 405 |
| Chain | Residue |
| A | GLY47 |
| A | LYS48 |
| A | ARG51 |
| A | GLN91 |
| A | ARG108 |
| A | TYR211 |
| A | PHE246 |
| A | GLN247 |
| A | ASP250 |
| A | 476406 |
| A | HOH523 |
| A | HOH550 |
| A | HOH597 |
| A | HOH600 |
| A | HOH604 |
| A | HOH640 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue 476 A 406 |
| Chain | Residue |
| A | PHE94 |
| A | ASP98 |
| A | MET101 |
| A | ASP102 |
| A | ARG107 |
| A | TRP164 |
| A | GLN167 |
| A | LYS207 |
| A | THR208 |
| A | ASP250 |
| A | LYS264 |
| A | CA401 |
| A | CA402 |
| A | CA403 |
| A | IPR405 |
| A | PEG407 |
| A | HOH536 |
| A | HOH553 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue PEG A 407 |
| Chain | Residue |
| A | ASP99 |
| A | SER104 |
| A | THR106 |
| A | ARG107 |
| A | ASP254 |
| A | LYS264 |
| A | ILE265 |
| A | GLY266 |
| A | 476406 |
| A | HOH504 |
| A | HOH619 |
| A | HOH669 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| B | ASP250 |
| B | 476405 |
| B | HOH527 |
| B | HOH573 |
| B | HOH595 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | ASP98 |
| B | ASP102 |
| B | CA403 |
| B | 476405 |
| B | HOH550 |
| B | HOH682 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 403 |
| Chain | Residue |
| B | ASP98 |
| B | ASP102 |
| B | CA402 |
| B | 476405 |
| B | HOH517 |
| B | HOH588 |
| B | HOH647 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue IPR B 404 |
| Chain | Residue |
| B | HOH535 |
| B | HOH553 |
| B | HOH555 |
| B | HOH576 |
| B | HOH601 |
| B | HOH611 |
| B | GLY47 |
| B | LYS48 |
| B | ARG51 |
| B | GLN91 |
| B | ARG108 |
| B | TYR211 |
| B | PHE246 |
| B | GLN247 |
| B | ASP250 |
| B | 476405 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for residue 476 B 405 |
| Chain | Residue |
| B | PHE94 |
| B | ASP98 |
| B | MET101 |
| B | ASP102 |
| B | ARG107 |
| B | GLN167 |
| B | LYS207 |
| B | THR208 |
| B | ASP250 |
| B | LYS264 |
| B | CA401 |
| B | CA402 |
| B | CA403 |
| B | IPR404 |
| B | HOH517 |
| B | HOH569 |
| B | HOH600 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for Di-peptide FME B 1 and ALA B 2 |
| Chain | Residue |
| B | HIS3 |
| B | MET4 |
| B | HOH645 |
| B | HOH661 |
| B | HOH713 |
Functional Information from PROSITE/UniProt
