6W7E
K2P2.1 (TREK-1), 30 mM K+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium channel subfamily K member 2 | polymer | 312 | 34303.9 | 2 | UniProt (P97438) Pfam (PF07885) | Mus musculus (Mouse) | Outward rectifying potassium channel protein TREK-1,TREK-1 K(+) channel subunit,Two pore potassium channel TPKC1 |
| 2 | C, D, J, K (A, B) | CADMIUM ION | non-polymer | 112.4 | 4 | Chemie (CD) | |||
| 3 | E (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 4 | F, L (A, B) | PENTANE | non-polymer | 72.1 | 2 | Chemie (LNK) | |||
| 5 | G, M, N (A, B) | N-OCTANE | non-polymer | 114.2 | 3 | Chemie (OCT) | |||
| 6 | H, P (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 7 | I (A) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 1 | Chemie (PIO) | |||
| 8 | O (B) | DODECANE | non-polymer | 170.3 | 1 | Chemie (D12) | |||
| 9 | Q (B) | HEXADECANE | non-polymer | 226.4 | 1 | Chemie (R16) |
Sequence modifications
A, B: 21 - 322 (UniProt: P97438)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | initiating methionine |
| Arg 84 | Lys 99 | conflict |
| Glu 85 | Gln 100 | conflict |
| Lys 86 | Thr 101 | conflict |
| Leu 88 | Ile 103 | conflict |
| Arg 89 | Ala 104 | conflict |
| Ala 90 | Gln 105 | conflict |
| Pro 92 | Ala 107 | conflict |
| Ser 95 | Asn 110 | conflict |
| Asp 96 | Ser 111 | conflict |
| Gln 97 | Thr 112 | conflict |
| Ala 119 | Asn 134 | conflict |
| Ala 300 | Ser 315 | conflict |
| Ala 306 | Glu 321 | conflict |
| Ser 323 | - | expression tag |
| Asn 324 | - | expression tag |
| Ser 325 | - | expression tag |
| Leu 326 | - | expression tag |
| Glu 327 | - | expression tag |
| Val 328 | - | expression tag |
| Leu 329 | - | expression tag |
| Phe 330 | - | expression tag |
| Gln 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68607.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2396.4 | |
| All* | Total formula weight | 71004.3 |
