6W5H
1.85 A resolution structure of Norovirus 3CL protease in complex with inhibitor 5d
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | 3C-LIKE PROTEASE | polymer | 187 | 19994.9 | 4 | UniProt (Q83883) In PDB | Norwalk virus (strain GI/Human/United States/Norwalk/1968) (Hu/NV/NV/1968/US) | |
2 | A, B, C, D | 2-(3-chlorophenyl)-2-methylpropyl [(2S)-3-cyclohexyl-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]carbamate | non-polymer | 522.1 | 4 | BIRD (PRD_002452) Chemie (TKP) | |||
3 | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 181 (UniProt: Q83883)
PDB | External Database | Details |
---|---|---|
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 79979.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2088.3 | |
All* | Total formula weight | 82068.0 |