6W4K
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with CC-90011
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1A | polymer | 659 | 73376.9 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (Human) | BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2 |
| 2 | B (B) | REST corepressor 1 | polymer | 132 | 15160.2 | 1 | UniProt (Q9UKL0) Pfam (PF20878) Pfam (PF00249) | Homo sapiens (Human) | Protein CoREST |
| 3 | C (A) | 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxyphenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile | non-polymer | 451.5 | 1 | Chemie (V0Y) | |||
| 4 | D (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 5 | E (A) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88537.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1237.0 | |
| All* | Total formula weight | 89774.2 |
