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6W3J

Crystal structure of the FAM46C/Plk4/Cep192 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Terminal nucleotidyltransferase 5Cpolymer34740035.81UniProt (Q5VWP2)
Pfam (PF07984)
Homo sapiens (Human)Non-canonical poly(A) polymerase FAM46C
2B
(B)
Serine/threonine-protein kinase PLK4polymer22325869.61UniProt (O00444)
Pfam (PF18190)
Pfam (PF18409)
Homo sapiens (Human)Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak
3C
(C)
Centrosomal protein of 192 kDapolymer222632.81UniProt (Q8TEP8)Homo sapiens (Human)Cep192/SPD-2
Sequence modifications
A: 14 - 358 (UniProt: Q5VWP2)
PDBExternal DatabaseDetails
Met 12-expression tag
Ala 13-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight68538.2
All*Total formula weight68538.2
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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