6W3C

Structure of phosphorylated apo IRE1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Serine/threonine-protein kinase/endoribonuclease IRE1	polymer	434	49801.4	4	UniProt (O75460) Pfam (PF00069) Pfam (PF06479)	Homo sapiens (Human)	Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a
2	E, F, G, H (A, B, C, D)	water	water		18.0	353	Chemie (HOH)

Sequence modifications

A, B, C, D: 547 - 977 (UniProt: O75460)

PDB	External Database	Details
Gly 978	-	expression tag
Asn 979	-	expression tag
Ser 980	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	199205.7
All*	Total formula weight	199205.7

*Water molecules are not included.