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6W2M

Abortive ternary complex crystal structure of DNA polymerase Beta with 8OG-dC base pair at the primer terminus and flipped out dA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(T)
Template Strandpolymer164885.21synthetic construct
3C
(P)
Primer Strandpolymer113374.21synthetic construct
4D
(D)
Downstream Primer Strandpolymer51536.01synthetic construct
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
7I, J
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
8K
(A)
[[[(2~{R},3~{S},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]methylphosphonic acidnon-polymer465.21Chemie (SFV)
9L, M, N, O
(A, T, P, D)
waterwater18.0446Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight48037.1
Non-Polymers*Number of molecules7
Total formula weight630.7
All*Total formula weight48667.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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