6W2L
Crystal structure of human dehydrodolichyl diphosphate synthase (NgBR/DHDDS) in complex with Mg and IPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dehydrodolichyl diphosphate synthase complex subunit DHDDS | polymer | 330 | 38455.2 | 1 | UniProt (Q86SQ9) Pfam (PF01255) | Homo sapiens (Human) | Cis-isoprenyltransferase,Cis-IPTase,Cis-prenyltransferase subunit hCIT,Epididymis tissue protein Li 189m |
| 2 | B (B) | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | polymer | 214 | 24086.4 | 1 | UniProt (Q96E22) Pfam (PF01255) | Homo sapiens (Human) | Cis-prenyltransferase subunit NgBR,Nogo-B receptor,NgBR,Nuclear undecaprenyl pyrophosphate synthase 1 homolog |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A) | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE | non-polymer | 246.1 | 2 | Chemie (IPE) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 2 - 330 (UniProt: Q86SQ9)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | - | expression tag |
| Met 253 | Val 253 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62541.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 516.5 | |
| All* | Total formula weight | 63058.1 |
