6W2J
CPS1 bound to allosteric inhibitor H3B-374
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Carbamoyl-phosphate synthase [ammonia], mitochondrial | polymer | 1500 | 165128.5 | 2 | UniProt (P31327) Pfam (PF00988) Pfam (PF00117) Pfam (PF02786) Pfam (PF02787) Pfam (PF02142) In PDB | Homo sapiens (Human) | Carbamoyl-phosphate synthetase I,CPSase I |
| 2 | A, B | (2-fluoranyl-4-methoxy-phenyl)-[(3~{R},5~{R})-4-(2-fluoranyl-4-methoxy-phenyl)carbonyl-3,5-dimethyl-piperazin-1-yl]methanone | non-polymer | 418.4 | 2 | Chemie (374) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 330257.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1029.8 | |
| All* | Total formula weight | 331286.8 |
