6W0Q
APE1 endonuclease product complex D148E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA-(apurinic or apyrimidinic site) lyase | polymer | 276 | 31202.6 | 2 | UniProt (P27695) Pfam (PF03372) In PDB | Homo sapiens (Human) | APEX nuclease,APEN,Apurinic-apyrimidinic endonuclease 1,APE-1,REF-1,Redox factor-1 |
| 2 | D | DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3') | polymer | 11 | 3210.1 | 1 | synthetic construct | ||
| 3 | P | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3') | polymer | 10 | 3061.0 | 1 | synthetic construct | ||
| 4 | V | DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 21 | 6465.2 | 1 | synthetic construct | ||
| 5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 8 | water | water | 18.0 | 451 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Glu 148 | Asp 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 75141.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 378.7 | |
| All* | Total formula weight | 75520.1 |
