6W01
The 1.9 A Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with a Citrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridylate-specific endoribonuclease | polymer | 370 | 41657.2 | 2 | UniProt (P0DTD1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | NSP15 endoribnuclease |
| 2 | BA, C, CA, D, E... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 22 | Chemie (EDO) | |||
| 3 | AA, G, H (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 4 | N, X (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 5 | DA, EA (A, B) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 347 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Gly -13 | - | expression tag |
| Val -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83314.5 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2068.1 | |
| All* | Total formula weight | 85382.6 |
