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6VZL

Crystal structure of human PPARgamma ligand binding domain in complex with GW1929

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27531449.52UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C, D
(A, B)
(2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acidnon-polymer495.62Chemie (EDK)
3E, F
(A, B)
waterwater18.0335Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62899.0
Non-Polymers*Number of molecules2
Total formula weight991.1
All*Total formula weight63890.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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