6VZ1

Cryo-EM structure of human diacylglycerol O-acyltransferase 1 complexed with acyl-CoA substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Diacylglycerol O-acyltransferase 1	polymer	488	55339.1	2	UniProt (O75907) Pfam (PF03062) In PDB	Homo sapiens (Human)	ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase,Retinol O-fatty-acyltransferase,Diglyceride acyltransferase
2	A, B	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate	non-polymer		718.0	4	Chemie (6OU)
3	A, B	S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)	non-polymer		1032.0	2	Chemie (3VV)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	110678.3
Non-Polymers*	Number of molecules	6
	Total formula weight	4935.9
All*	Total formula weight	115614.2

*Water molecules are not included.