6VXX

Structure of the SARS-CoV-2 spike glycoprotein (closed state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1281	141532.8	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	S glycoprotein,E2,Peplomer protein,SARS-CoV-2 spike glycoprotein
2	D, E, F, G, H... (D, E, F, G, H...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	15	In PDB GlyTouCan (G42666HT)
3	AA, BA, CA, DA, EA... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	33	Chemie (NAG)

Sequence modifications

A, B, C: 14 - 1211 (UniProt: P0DTC2)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ile -16	-	expression tag
Leu -15	-	expression tag
Pro -14	-	expression tag
Ser -13	-	expression tag
Pro -12	-	expression tag
Gly -11	-	expression tag
Met -10	-	expression tag
Pro -9	-	expression tag
Ala -8	-	expression tag
Leu -7	-	expression tag
Leu -6	-	expression tag
Ser -5	-	expression tag
Leu -4	-	expression tag
Val -3	-	expression tag
Ser -2	-	expression tag
Leu -1	-	expression tag
Leu 0	-	expression tag
Ser 1	-	expression tag
Val 2	-	expression tag
Leu 3	-	expression tag
Leu 4	-	expression tag
Met 5	-	expression tag
Gly 6	-	expression tag
Cys 7	-	expression tag
Val 8	-	expression tag
Ala 9	-	expression tag
Glu 10	-	expression tag
Thr 11	-	expression tag
Gly 12	-	expression tag
Thr 13	-	expression tag
Ser 682	Arg 682	conflict
Gly 683	Arg 683	conflict
Gly 685	Arg 685	conflict
Pro 986	Lys 986	conflict
Pro 987	Val 987	conflict
Gly 1212	-	expression tag
Ser 1213	-	expression tag
Gly 1214	-	expression tag
Arg 1215	-	expression tag
Glu 1216	-	expression tag
Asn 1217	-	expression tag
Leu 1218	-	expression tag
Tyr 1219	-	expression tag
Phe 1220	-	expression tag
Gln 1221	-	expression tag
Gly 1222	-	expression tag
Gly 1223	-	expression tag
Gly 1224	-	expression tag
Gly 1225	-	expression tag
Ser 1226	-	expression tag
Gly 1227	-	expression tag
Tyr 1228	-	expression tag
Ile 1229	-	expression tag
Pro 1230	-	expression tag
Glu 1231	-	expression tag
Ala 1232	-	expression tag
Pro 1233	-	expression tag
Arg 1234	-	expression tag
Asp 1235	-	expression tag
Gly 1236	-	expression tag
Gln 1237	-	expression tag
Ala 1238	-	expression tag
Tyr 1239	-	expression tag
Val 1240	-	expression tag
Arg 1241	-	expression tag
Lys 1242	-	expression tag
Asp 1243	-	expression tag
Gly 1244	-	expression tag
Glu 1245	-	expression tag
Trp 1246	-	expression tag
Val 1247	-	expression tag
Leu 1248	-	expression tag
Leu 1249	-	expression tag
Ser 1250	-	expression tag
Thr 1251	-	expression tag
Phe 1252	-	expression tag
Leu 1253	-	expression tag
Gly 1254	-	expression tag
His 1255	-	expression tag
His 1256	-	expression tag
His 1257	-	expression tag
His 1258	-	expression tag
His 1259	-	expression tag
His 1260	-	expression tag
His 1261	-	expression tag
His 1262	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	424598.4
Branched	Number of molecules	15
	Total formula weight	6366.0
Non-Polymers*	Number of molecules	33
	Total formula weight	7299.9
All*	Total formula weight	438264.3

*Water molecules are not included.