6VXK

Cryo-EM Structure of the full-length A39R/PlexinC1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Semaphorin-like protein 139	polymer	398	45330.2	2	UniProt (Q8JL80) Pfam (PF01403) In PDB	Ectromelia virus (strain Moscow) (ECTV)
2	B, D	Plexin-C1	polymer	1545	173487.0	2	UniProt (O60486) Pfam (PF01437) Pfam (PF01833) Pfam (PF08337) Pfam (PF20170) In PDB	Homo sapiens (Human)	Virus-encoded semaphorin protein receptor
3	A, B, C, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	18	Chemie (NAG)

Sequence modifications

A, C: 15 - 399 (UniProt: Q8JL80)

PDB	External Database	Details
Glu 12	-	expression tag
Leu 13	-	expression tag
Glu 14	-	expression tag
Gly 400	-	expression tag
Thr 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
His 409	-	expression tag

B, D: 35 - 1568 (UniProt: O60486)

PDB	External Database	Details
Gly 1569	-	expression tag
Thr 1570	-	expression tag
Ser 1571	-	expression tag
Ser 1572	-	expression tag
Gly 1573	-	expression tag
Leu 1574	-	expression tag
Glu 1575	-	expression tag
Val 1576	-	expression tag
Leu 1577	-	expression tag
Phe 1578	-	expression tag
Gln 1579	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	437634.4
Non-Polymers*	Number of molecules	18
	Total formula weight	3981.7
All*	Total formula weight	441616.1

*Water molecules are not included.