6VWH

Leg region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain	polymer	952	108937.2	2	UniProt (P08069) UniProt (P03069) Pfam (PF01030) Pfam (PF00757) Pfam (PF07716)	Homo sapiens (Human)	Insulin-like growth factor I receptor,IGF-I receptor,Amino acid biosynthesis regulatory protein

Sequence modifications

A, B: 1 - 905 (UniProt: P08069)
A, B: 906 - 938 (UniProt: P03069)

PDB	External Database	Details
Ser 939	-	expression tag
Ser 940	-	expression tag
Ser 941	-	expression tag
Glu 942	-	expression tag
Gln 943	-	expression tag
Lys 944	-	expression tag
Leu 945	-	expression tag
Ile 946	-	expression tag
Ser 947	-	expression tag
Glu 948	-	expression tag
Glu 949	-	expression tag
Asp 950	-	expression tag
Leu 951	-	expression tag
Asn 952	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	217874.5
All*	Total formula weight	217874.5

*Water molecules are not included.