6VUG
Diabody bound to a Reverse Transcriptase Aptamer Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Reverse transcriptase/ribonuclease H | polymer | 555 | 63875.1 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 (HIV-1) | Gag-Pol polyprotein, Pr160Gag-Pol |
2 | B | REVERSE TRANSCRIPTASE P51 | polymer | 444 | 51928.6 | 1 | UniProt (A0A076Q3N8) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) UniProt (by SIFTS) (P03366) In PDB | Human immunodeficiency virus 1 (HIV-1) | |
3 | C | Light chain variable fragment | polymer | 120 | 13249.6 | 1 | Homo sapiens (Human) | ||
4 | D | Heavy chain variable fragment | polymer | 124 | 13185.6 | 1 | Homo sapiens (Human) | ||
5 | E | DNA (38-MER) | polymer | 38 | 11748.5 | 1 | Human immunodeficiency virus 1 (HIV-1) | ||
6 | B, C | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
7 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) |
Sequence modifications
A: 1 - 555 (UniProt: P03366)
B: 1 - 428 (UniProt: A0A076Q3N8)
PDB | External Database | Details |
---|---|---|
Ser 280 | Cys 879 | conflict |
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
Ala -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
Ala -7 | - | expression tag |
Leu -6 | - | expression tag |
Glu -5 | - | expression tag |
Val -4 | - | expression tag |
Leu -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Lys 172 | Arg 339 | engineered mutation |
Ser 280 | Cys 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 153987.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1148.8 | |
All* | Total formula weight | 155136.3 |