6VTA

Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with amikacin and acetyl-CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Aminoglycoside 2'-N-acetyltransferase	polymer	181	20391.0	2	UniProt (Q52424) Pfam (PF13527)	Providencia stuartii	AAC(2')-Ia
2	C, E (A, B)	ACETYL COENZYME *A	non-polymer		809.6	2	Chemie (ACO)
3	D, F (A, B)	(2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide	non-polymer		585.6	2	Chemie (AKN)
4	G, H (A, B)	water	water		18.0	480	Chemie (HOH)

Sequence modifications

A, B: 1 - 178 (UniProt: Q52424)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40781.9
Non-Polymers*	Number of molecules	4
	Total formula weight	2790.3
All*	Total formula weight	43572.3

*Water molecules are not included.