6VSD
Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-((thiophen-2-ylthio)methyl)benzoic acid (fragment 13)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydrofolate reductase | polymer | 161 | 17893.3 | 2 | UniProt (P9WNX1) Pfam (PF00186) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | A, B | 3-(thiophen-2-ylsulfanylmethyl)benzoic acid | non-polymer | 250.3 | 2 | Chemie (JBB) | |||
| 3 | A, B | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | A, B | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | water | water | 18.0 | 310 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2296.4 | |
| All* | Total formula weight | 38083.0 |
