6VS8
Mycobacterium tuberculosis dihydrofolate reductase in complex with ethyl 2-methyl thiazole-4-carboxylate(fragment 3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 161 | 17893.3 | 2 | UniProt (A0A0E8UVJ4) Pfam (PF00186) UniProt (by SIFTS) (P9WNX1) | Mycobacterium tuberculosis | |
| 2 | C, H (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 3 | D, I (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 4 | E, J, K (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | F, L (A, B) | ethyl 2-methyl-1,3-thiazole-4-carboxylate | non-polymer | 171.2 | 2 | Chemie (RJY) | |||
| 6 | G, M, N, O (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 7 | P, Q (A, B) | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2616.3 | |
| All* | Total formula weight | 38402.9 |
