6VRG
Structure of HIV-1 integrase with native amino-terminal sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Integrase | polymer | 212 | 23319.5 | 4 | UniProt (F2WR39) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | E, H, K, N (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | F, I, L, O (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | G, J, M, P (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 212 (UniProt: F2WR39)
| PDB | External Database | Details |
|---|---|---|
| Asp 131 | Trp 131 | engineered mutation |
| Asp 139 | Phe 139 | engineered mutation |
| Lys 185 | Phe 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93278.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 797.9 | |
| All* | Total formula weight | 94075.9 |
