6VRA
Anthrax octamer prechannel bound to full-length edema factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Protective antigen | polymer | 735 | 82511.3 | 4 | UniProt (P13423) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) Pfam (PF20835) In PDB | Bacillus anthracis | PA,Anthrax toxins translocating protein,PA-83,PA83 |
2 | B, D, F, H | Protective antigen | polymer | 735 | 82639.7 | 4 | UniProt (P13423) Pfam (PF20835) Pfam (PF07691) Pfam (PF03495) Pfam (PF17475) Pfam (PF17476) In PDB | Bacillus anthracis | PA,Anthrax toxins translocating protein,PA-83,PA83 |
3 | I, J, K, L | Calmodulin-sensitive adenylate cyclase | polymer | 767 | 88955.6 | 4 | UniProt (P40136) Pfam (PF07737) Pfam (PF03497) Pfam (PF20850) In PDB | Bacillus anthracis | ATP pyrophosphate-lyase,Adenylyl cyclase,Anthrax edema toxin adenylate cyclase component,Edema factor,EF |
4 | H, A, B, C, D... | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) |
Sequence modifications
A, C, E, G: 1 - 735 (UniProt: P13423)
B, D, F, H: 1 - 735 (UniProt: P13423)
PDB | External Database | Details |
---|---|---|
Asp 121 | Asn 153 | conflict |
Leu 161 | Arg 193 | conflict |
Glu 162 | Lys 194 | conflict |
Val 163 | - | insertion |
Leu 164 | - | insertion |
Phe 165 | - | insertion |
Gln 166 | Lys 195 | conflict |
Gly 167 | Arg 196 | conflict |
Gly 245 | Lys 274 | engineered mutation |
Asn 252 | Arg 281 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Leu 161 | Arg 193 | conflict |
Glu 162 | Lys 194 | conflict |
Val 163 | - | insertion |
Leu 164 | - | insertion |
Phe 165 | - | insertion |
Gln 166 | Lys 195 | conflict |
Gly 167 | Arg 196 | conflict |
Lys 512 | Asp 541 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 1016426.3 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 641.2 | |
All* | Total formula weight | 1017067.6 |