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6VP0

Human Diacylglycerol Acyltransferase 1 in complex with oleoyl-CoA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(C, E)
Diacylglycerol O-acyltransferase 1polymer48855339.12UniProt (O75907)
Pfam (PF03062)
Homo sapiens (Human)ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase,Retinol O-fatty-acyltransferase,Diglyceride acyltransferase
2C, F, I, L
(C, E)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.14Chemie (POV)
3D, E, J, K
(C, E)
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serinenon-polymer792.14Chemie (P5S)
4G, M
(C, E)
S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)non-polymer1032.02Chemie (3VV)
5H, N
(C, E)
Lauryl Maltose Neopentyl Glycolnon-polymer1005.22Chemie (AV0)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight110678.3
Non-Polymers*Number of molecules12
Total formula weight10282.9
All*Total formula weight120961.2
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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