6VOU
Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with acetylated-plazomicin and CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aminoglycoside 2'-N-acetyltransferase | polymer | 179 | 20246.8 | 2 | UniProt (Q52424) Pfam (PF13527) | Providencia stuartii | AAC(2')-Ia |
| 2 | C, H (A, B) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 3 | D (A) | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 4 | E, F, I (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 3 | Chemie (MPD) | |||
| 5 | G, J (A, B) | (2S)-N-[(1R,2S,3S,4R,5S)-4-{[(2S,3R)-3-(acetylamino)-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-yl]oxy}-5-amino-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-4-amino-2-hydroxybutanamide | non-polymer | 634.7 | 2 | Chemie (PZC) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 178 (UniProt: Q52424)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40493.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3409.2 | |
| All* | Total formula weight | 43902.9 |
