6VND
Quaternary Complex of human dihydroorotate dehydrogenase (DHODH) with flavin mononucleotide (FMN), orotic acid and AG-636
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 368 | 39913.6 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (Human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | 1-methyl-5-(2'-methyl[1,1'-biphenyl]-4-yl)-1H-benzotriazole-7-carboxylic acid | non-polymer | 343.4 | 1 | Chemie (R4P) | |||
| 3 | C, D (A) | UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 215.4 | 2 | Chemie (DET) | |||
| 4 | E, F (A) | DECYLAMINE-N,N-DIMETHYL-N-OXIDE | non-polymer | 201.3 | 2 | Chemie (DDQ) | |||
| 5 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | H, I, J (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 7 | K (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 8 | L (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 9 | M, N, O (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 10 | P, Q, R, S, T... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 11 | V (A) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 29 - 395 (UniProt: Q02127)
| PDB | External Database | Details |
|---|---|---|
| Gly 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39913.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2623.4 | |
| All* | Total formula weight | 42537.0 |
