6VLR
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, H, G) | Envelope glycoprotein gp120 | polymer | 475 | 53268.4 | 3 | UniProt (Q2N0S6) Pfam (PF00516) | Human immunodeficiency virus 1 | BG505 SOSIP.v5.2 gp120 |
| 2 | B, D, F (B, J, I) | BG505 SOSIPv5.2 gp41 | polymer | 153 | 17178.5 | 3 | UniProt (Q2N0S6) Pfam (PF00517) | Human immunodeficiency virus 1 (HIV-1) | Env polyprotein |
| 3 | G, I, K (C, D, E) | PGT122 Fab Heavy Chain | polymer | 132 | 14838.7 | 3 | Homo sapiens | ||
| 4 | H, J, L (L, K, M) | PGT122 Fab Light Chain | polymer | 106 | 11510.6 | 3 | Homo sapiens | ||
| 5 | M (F) | RM20E1 Fab Heavy Chain | polymer | 123 | 13878.6 | 1 | Macaca mulatta | ||
| 6 | N (N) | RM20E1 Fab Kappa Chain | polymer | 112 | 12370.8 | 1 | Macaca mulatta | ||
| 7 | CA, DA, O, P, R... (c, d, O, P, R...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
| 8 | EA, Q, U, Y (e, Q, U, Y) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 4 | In PDB GlyTouCan (G22768VO) | |||
| 9 | S, Z (S, Z) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 10 | AA, FA, T (a, f, T) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 11 | BA, GA (b, g) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 12 | AB, BB, CB, DB, EB... (G, I, A, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
A, H, G: 31 - 507 (UniProt: Q2N0S6)
B, J, I: 512 - 664 (UniProt: Q2N0S6)
| PDB | External Database | Details |
|---|---|---|
| Lys 64 | Glu 63 | conflict |
| Cys 73 | Ala 72 | conflict |
| Trp 316 | Ala 313 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 501 | Ala 498 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | conflict |
| Cys 561 | Ala 558 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 316638.1 | |
| Branched | Number of molecules | 19 |
| Total formula weight | 12927.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 334874.9 |
