6VLK

A varicella-zoster virus glycoprotein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Envelope glycoprotein B	polymer	744	84922.4	2	UniProt (Q4JR05) Pfam (PF17416) Pfam (PF17417) Pfam (PF00606)	Varicella-zoster virus (strain Oka vaccine) (HHV-3)	gB
2	C (C)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
3	D (D)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
4	E (E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	F, G, H (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	I, J (A, B)	water	water		18.0	171	Chemie (HOH)

Sequence modifications

A, B: 1 - 736 (UniProt: Q4JR05)

PDB	External Database	Details
Gly 180	Trp 180	engineered mutation
Gly 185	Tyr 185	engineered mutation
Gly 491	Arg 491	engineered mutation
Gly 493	Arg 493	engineered mutation
Gly 494	Arg 494	engineered mutation
Gly 737	-	expression tag
Ser 738	-	expression tag
His 739	-	expression tag
His 740	-	expression tag
His 741	-	expression tag
His 742	-	expression tag
His 743	-	expression tag
His 744	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	169844.9
Branched	Number of molecules	3
	Total formula weight	2570.3
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	173078.8

*Water molecules are not included.