6VLD

Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H	Alpha-(1,6)-fucosyltransferase	polymer	481	55748.0	4	UniProt (Q9BYC5) Pfam (PF19745) Pfam (PF14604) In PDB	Homo sapiens (Human)	Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase
2	C, D, E, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1317.2	4	In PDB GlyTouCan (G39213VZ)
3	A, B, G, H	ASPARAGINE	non-polymer		132.1	4	Chemie (ASN)
4	A, B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
5	A, B, G, H	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
6		water	water		18.0	628	Chemie (HOH)

Sequence modifications

A, B, G, H: 105 - 575 (UniProt: Q9BYC5)

PDB	External Database	Details
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag
His 579	-	expression tag
His 580	-	expression tag
His 581	-	expression tag
His 582	-	expression tag
His 583	-	expression tag
His 584	-	expression tag
His 585	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	222991.9
Branched	Number of molecules	4
	Total formula weight	5268.8
Non-Polymers*	Number of molecules	18
	Total formula weight	2567.6
All*	Total formula weight	230828.4

*Water molecules are not included.