6VLD
Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, G, H) | Alpha-(1,6)-fucosyltransferase | polymer | 481 | 55748.0 | 4 | UniProt (Q9BYC5) Pfam (PF19745) Pfam (PF14604) | Homo sapiens (Human) | Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase |
| 2 | E, F, G, H (C, D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 4 | In PDB GlyTouCan (G39213VZ) | |||
| 3 | I, O, R, U (A, B, G, H) | ASPARAGINE | non-polymer | 132.1 | 4 | Chemie (ASN) | |||
| 4 | J, P (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | K, L, M, N, Q... (A, B, G, H) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 6 | AA, BA, CA, DA (A, B, G, H) | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B, G, H: 105 - 575 (UniProt: Q9BYC5)
| PDB | External Database | Details |
|---|---|---|
| His 576 | - | expression tag |
| His 577 | - | expression tag |
| His 578 | - | expression tag |
| His 579 | - | expression tag |
| His 580 | - | expression tag |
| His 581 | - | expression tag |
| His 582 | - | expression tag |
| His 583 | - | expression tag |
| His 584 | - | expression tag |
| His 585 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222991.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 5268.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2567.6 | |
| All* | Total formula weight | 230828.4 |
