6VLD
Crystal structure of human alpha 1,6-fucosyltransferase, FUT8 bound to GDP and A2SGP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, G, H | Alpha-(1,6)-fucosyltransferase | polymer | 481 | 55748.0 | 4 | UniProt (Q9BYC5) Pfam (PF19745) Pfam (PF14604) In PDB | Homo sapiens (Human) | Alpha1-6FucT,Fucosyltransferase 8,GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,GDP-fucose--glycoprotein fucosyltransferase,Glycoprotein 6-alpha-L-fucosyltransferase |
2 | C, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 4 | In PDB GlyTouCan (G39213VZ) | |||
3 | A, B, G, H | ASPARAGINE | non-polymer | 132.1 | 4 | Chemie (ASN) | |||
4 | A, B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
5 | A, B, G, H | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
6 | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B, G, H: 105 - 575 (UniProt: Q9BYC5)
PDB | External Database | Details |
---|---|---|
His 576 | - | expression tag |
His 577 | - | expression tag |
His 578 | - | expression tag |
His 579 | - | expression tag |
His 580 | - | expression tag |
His 581 | - | expression tag |
His 582 | - | expression tag |
His 583 | - | expression tag |
His 584 | - | expression tag |
His 585 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 222991.9 | |
Branched | Number of molecules | 4 |
Total formula weight | 5268.8 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2567.6 | |
All* | Total formula weight | 230828.4 |